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Pure and Applied Chemistry

The Scientific Journal of IUPAC

Ed. by Burrows, Hugh / Weir, Ron / Stohner, Jürgen

12 Issues per year


IMPACT FACTOR 2016: 2.626
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CiteScore 2016: 2.45

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ISSN
1365-3075
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Volume 74, Issue 12 (Jan 2002)

Issues

Advances in biocatalytic synthesis. Enzyme-triggered asymmetric cascade reactions

S. M. Glueck
  • Corresponding author
  • Department of Chemistry, Organic and Bioorganic Chemistry, University of Graz, Heinrichstrasse 28, A-8010 Graz, Austria
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/ S. F. Mayer
  • Corresponding author
  • Department of Chemistry, Organic and Bioorganic Chemistry, University of Graz, Heinrichstrasse 28, A-8010 Graz, Austria
  • Other articles by this author:
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/ Wolfgang Kroutil
  • Corresponding author
  • Department of Chemistry, Organic and Bioorganic Chemistry, University of Graz, Heinrichstrasse 28, A-8010 Graz, Austria
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/ K. Faber
  • Corresponding author
  • Department of Chemistry, Organic and Bioorganic Chemistry, University of Graz, Heinrichstrasse 28, A-8010 Graz, Austria
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Published Online: 2009-01-01 | DOI: https://doi.org/10.1351/pac200274122253

Organic compounds can be transformed through enzyme-triggered domino (or cascade) reactions via several (inseparable) consecutive steps in an asymmetric fashion to yield nonracemic products. Despite the fact that these sequences often involve the occurrence of highly reactive unstable intermediates, the overall efficiency of these processes can be high, provided that the reaction rates of the individual steps match each other in order to minimize side reactions.

Conference

IUPAC Workshop, Impact of Scientific Developments on the Chemical Weapons Convention, Bergen, Norway, 2002-06-30–2002-07-03

About the article

Published Online: 2009-01-01

Published in Print: 2002-01-01


Citation Information: Pure and Applied Chemistry, ISSN (Online) 1365-3075, ISSN (Print) 0033-4545, DOI: https://doi.org/10.1351/pac200274122253.

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