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Pure and Applied Chemistry

The Scientific Journal of IUPAC

Ed. by Burrows, Hugh / Stohner, Jürgen


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Volume 74, Issue 3

Issues

Plasma sterilization. Methods and mechanisms

Michel Moisan
  • Corresponding author
  • Groupe de physique des plasmas, Université de Montréal, B.P. 6128, Succursale Centre-ville, Montréal H3C 3J7, Québec, Canada
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/ Jean Barbeau
  • Corresponding author
  • Laboratoire de Microbiologie et d'Immunologie, Faculté de Médecine Dentaire, Université de Montréal, C.P. 6128, Succursale Centre-ville, Montréal H3C 3J7, Québec, Canada
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/ Marie-Charlotte Crevier
  • Corresponding author
  • Groupe de Recherche en Biomécanique et Biomatériaux (GRBB), Département de Génie Biomédical, École Polytechnique de Montréal, C.P. 6079, Succursale Centre-ville, Montréal H3C 3A7, Québec, Canada
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/ Jacques Pelletier
  • Corresponding author
  • Laboratoire d'Électrostatique et de Matériaux Diélectriques, Centre National de la Recherche Scientifique et Université Joseph Fourier, B.P. 166, 38042-Grenoble Cedex 9, France
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/ Nicolas Philip
  • Corresponding author
  • Groupe de physique des plasmas, Université de Montréal, B.P. 6128, Succursale Centre-ville, Montréal H3C 3J7, Québec, Canada
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/ Bachir Saoudi
  • Corresponding author
  • Groupe de physique des plasmas, Université de Montréal, B.P. 6128, Succursale Centre-ville, Montréal H3C 3J7, Québec, Canada
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Published Online: 2009-01-01 | DOI: https://doi.org/10.1351/pac200274030349

Utilizing a plasma to achieve sterilization is a possible alternative to conventional sterilization means as far as sterilization of heat-sensitive materials and innocuity of sterilizing agents are concerned. A major issue of plasma sterilization is the respective roles of ultraviolet (UV) photons and reactive species such as atomic and molecular radicals. At reduced gas pressure (£10 torr) and in mixtures containing oxygen, the UV photons dominate the inactivation process, with a significant contribution of oxygen atoms as an erosion agent. Actually, as erosion of the spore progresses, the number of UV photons successfully interacting with the genetic material increases. The different physicochemical processes at play during plasma sterilization are identified and analyzed, based on the specific characteristics of the spore survival curves.

Conference

International Symposium on Plasma Chemistry, International Symposium on Plasma Chemistry, ISPC, Plasma Chemistry, 15th, Orléans, France, 2001-07-09–2001-07-13

About the article

Published Online: 2009-01-01

Published in Print: 2002-01-01


Citation Information: Pure and Applied Chemistry, Volume 74, Issue 3, Pages 349–358, ISSN (Online) 1365-3075, ISSN (Print) 0033-4545, DOI: https://doi.org/10.1351/pac200274030349.

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