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Pure and Applied Chemistry

The Scientific Journal of IUPAC

Ed. by Burrows, Hugh / Stohner, Jürgen

IMPACT FACTOR 2017: 5.294

CiteScore 2017: 3.42

SCImago Journal Rank (SJR) 2017: 1.212
Source Normalized Impact per Paper (SNIP) 2017: 1.546

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Volume 75, Issue 5


Endocrine disruptors in the environment (IUPAC Technical Report)

J. Lintelmann
  • Corresponding author
  • GSF National Research Center for Environmental Chemistry, P.O. Box 1129, D-85758, Neuherberg, Germany
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/ A. Katayama
  • Corresponding author
  • Research Center for Advanced Waste and Emission Management, Nagoya University, Chikusa, Nagoya, 464-86003, Japan
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/ N. Kurihara
  • Corresponding author
  • c/o Emeritus Club, Kyoto University, 103-5 Tanaka Monzen-cho, Sakyo-ku, Kyoto, 606-8225 Japan
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/ L. Shore
  • Corresponding author
  • Department of Hormone Research, Kimron Veterinary Institute, Bet Dagan, P.O. Box 12, Israel
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/ A. Wenzel
  • Corresponding author
  • Fraunhofer Institute Umweltchemie and Ökotoxikolgie, Auf dem Aberg 1, D-57392, Schmallenberg, Germany
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Published Online: 2009-01-01 | DOI: https://doi.org/10.1351/pac200375050631

Many chemical substances of natural or anthropogenic origin are suspected or known to be endocrine disruptors, which can influence the endocrine system of life. This observation has led to increased interest on the part of the public and the media, as well as to a steep rise of research activities in the scientific community. New papers and results are presented so fast that it is impossible to give a complete review of this emerging research field. Therefore, this paper tries to give insight into some topics of the great scope of endocrine disruptors in the environment. To get a general idea of the biochemical and biological background, some parts of the endocrine systems of mammalians and nonmammalians are explained. The sections that follow describe important mechanisms of endocrine disruption such as interactions with hormone receptors. Test strategies for anthropogenic chemicals on various organisms are critically reviewed with respect to their problems and gaps concerning endocrine disruptors. The main emphasis of the paper is on the chemical substances suspected or known to be endocrine disruptors. To get a better comprehension of their behavior in the environment, physicochemical data such as water solubility or Kow, as well as information about their use and/or function are reviewed and compared. The main routes of exposure for most chemicals are shortly described, and data about concentrations in the environment (soil/sediment, water) are detailed.

Project Year: 1997, Project Code: 630/26/97

About the article

Published Online: 2009-01-01

Published in Print: 2003-01-01

Citation Information: Pure and Applied Chemistry, Volume 75, Issue 5, Pages 631–681, ISSN (Online) 1365-3075, ISSN (Print) 0033-4545, DOI: https://doi.org/10.1351/pac200375050631.

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Reviews on Environmental Health, 2010, Volume 25, Number 4
Erik W. Allen
Journal of Environmental Engineering and Science, 2008, Volume 7, Number 2, Page 123
P. Pocostales, P. Álvarez, and F.J. Beltrán
Chemical Engineering Journal, 2011, Volume 168, Number 3, Page 1289
Fernando G. Braga, Sandra Pinto, and Maria Cristina G. Antunes
Microchimica Acta, 2011, Volume 173, Number 1-2, Page 111
Gro D. Villanger, Bjørn M. Jenssen, Rita R. Fjeldberg, Robert J. Letcher, Derek C.G. Muir, Maja Kirkegaard, Christian Sonne, and Rune Dietz
Environment International, 2011, Volume 37, Number 4, Page 694
Tae-Hee Kim, Yeon-pyo Hong, Hae-Hyeog Lee, Soo-Ho Chung, Yun-jung Yang, Sang-yon Kim, Young Lim Kho, and Jun-Mo Kim
Korean Journal of Obstetrics, 2011, Volume 54, Number 3, Page 140
M. S. Marty, E. W. Carney, and J. C. Rowlands
Toxicological Sciences, 2011, Volume 120, Number Supplement 1, Page S93
Maren Ortiz-Zarragoitia, Larraitz Garmendia, María Carmen Barbero, Teresa Serrano, Ionan Marigómez, and Miren P. Cajaraville
J. Environ. Monit., 2011, Volume 13, Number 1, Page 84
C. Maduka Ignatius, E. Ezeonu Francis, E. Neboh Emeka, N. Shu Elvis, and J. Ikekpeazu Ebele
Bulletin of Environmental Contamination and Toxicology, 2010, Volume 85, Number 5, Page 534
Jae-Han Shim, Mi-Ra Kim, Edward Topp, Jeong-Heui Choi, and Iqbal Rouf Mamun
Korean Journal of Environmental Agriculture, 2008, Volume 27, Number 4, Page 447
Sung-Woo Lee, Hwa-Young Son, Won-Kee Yoon, Ju-Young Jung, Bae-Keun Park, Eun-Sang Cho, Sang-Joon Park, Tae-Hwan Kim, and Si-Yun Ryu
Biomolecules and Therapeutics, 2010, Volume 18, Number 3, Page 286
Cláudia Ribeiro, Miguel Ângelo Pardal, Maria Elizabeth Tiritan, Eduardo Rocha, Rui Miguel Margalho, and Maria João Rocha
Environmental Monitoring and Assessment, 2009, Volume 159, Number 1-4, Page 415
Vera Pacáková, Lucie Loukotková, Zuzana Bosáková, and Karel Štulík
Journal of Separation Science, 2009, Page NA
Cláudia Ribeiro, Maria Elizabeth Tiritan, Eduardo Rocha, and Maria João Rocha
Archives of Environmental Contamination and Toxicology, 2009, Volume 56, Number 1, Page 1
Zhaosheng Fan, Francis X. M. Casey, Heldur Hakk, and Gerald L. Larsen
Water Resources Research, 2008, Volume 44, Number 8
Luisa Patrolecco, Silvio Capri, Silvia De Angelis, Romano Pagnotta, Stefano Polesello, and Sara Valsecchi
Water, Air, and Soil Pollution, 2006, Volume 172, Number 1-4, Page 151
Helmut Greim
Angewandte Chemie International Edition, 2005, Volume 44, Number 35, Page 5568
Herlinde Noppe, Katia De Wasch, Sofie Poelmans, Nathalie Van Hoof, Tim Verslycke, Colin R. Janssen, and Hubert F. De Brabander
Analytical and Bioanalytical Chemistry, 2005, Volume 382, Number 1, Page 91
Catherine Pringle
Aquatic Conservation: Marine and Freshwater Ecosystems, 2003, Volume 13, Number 6, Page 467
Angela Lorenzen, John G. Hendel, Kenneth L. Conn, Shabtai Bittman, Allan B. Kwabiah, George Lazarovitz, Daniel Massé, Tim A. McAllister, and Edward Topp
Environmental Toxicology, 2004, Volume 19, Number 3, Page 216
K. Haarstad and G. H. Ludvigsen
Ground Water Monitoring & Remediation, 2007, Volume 27, Number 3, Page 75
Jim Rasmussen, Jens Aamand, Per Rosenberg, Ole S Jacobsen, and Sebastian R Sørensen
Pest Management Science, 2005, Volume 61, Number 9, Page 829

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