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Pure and Applied Chemistry

The Scientific Journal of IUPAC

Ed. by Burrows, Hugh / Stohner, Jürgen

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Volume 77, Issue 7


Ring-closing metathesis: A facile construct for alkaloid synthesis

Stephen F. Martin
  • Corresponding author
  • Department of Chemistry and Biochemistry, The University of Texas, Austin, TX 78712, USA
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Published Online: 2009-01-01 | DOI: https://doi.org/10.1351/pac200577071207

Ring-closing metathesis has been found to be a highly effective reaction for the synthesis of functionalized, bridged nitrogen heterocycles. The utility of the process has been established in several case studies, including a facile synthesis of the tropane ring system and efficient, enantioselective syntheses of the natural products (–)-peduncularine and (+)-anatoxin-a.

Keywords: alkaloids; enantioselective; heterocycles; ring-closing metathesis; stereoselective


International Conference on Organic Synthesis (ICOS-15), International Conference on Organic Synthesis, ICOS, Organic Synthesis, 15th, Nagoya, Japan, 2004-08-01–2004-08-06

About the article

Published Online: 2009-01-01

Published in Print: 2005-01-01

Citation Information: Pure and Applied Chemistry, Volume 77, Issue 7, Pages 1207–1212, ISSN (Online) 1365-3075, ISSN (Print) 0033-4545, DOI: https://doi.org/10.1351/pac200577071207.

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