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Pure and Applied Chemistry

The Scientific Journal of IUPAC

Ed. by Burrows, Hugh / Weir, Ron / Stohner, Jürgen

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Volume 83, Issue 3


1,5-Polyols: Challenging motifs for configurational assignment and synthesis

Gregory K. Friestad / Gopeekrishnan Sreenilayam
Published Online: 2011-01-29 | DOI: https://doi.org/10.1351/PAC-CON-10-10-19

Despite the well-established methods for stereochemical assignments and synthesis of 1,3-diols, the corresponding 1,5-diols and -polyols present specific challenges which remain unsolved. This article highlights some new strategies and methodologies specifically designed for the 1,5-diol motif.

Keywords: alcohols; asymmetric synthesis; coupling reactions; natural products; polyketides


International Conference on Organic Synthesis (ICOS-18), International Conference on Organic Synthesis, ICOS, Organic Synthesis, 18th, Bergen, Norway, 2010-08-01–2010-08-06


About the article

Published Online: 2011-01-29

Published in Print: 2011-01-31

Citation Information: Pure and Applied Chemistry, Volume 83, Issue 3, Pages 461–478, ISSN (Online) 1365-3075, ISSN (Print) 0033-4545, DOI: https://doi.org/10.1351/PAC-CON-10-10-19.

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