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Pure and Applied Chemistry

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Volume 83, Issue 5

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Glossary of terms used in biomolecular screening (IUPAC Recommendations 2011)

John Proudfoot
  • Corresponding author
  • Boehringer Ingelheim Pharmaceuticals, Inc., 900 Ridgebury Road, Ridgefield, CT 06877, USA
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 / Olivier Nosjean
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  • Servier Research Institute, 125 Chemin de Ronde, 78290 Croissy-sur-Seine, France
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 / Jan Blanchard
  • Corresponding author
  • McMaster HTS Laboratory, Department of Biochemistry and Biomedical Sciences, McMaster University, HSC 4N45-D, 1200 Main St. West, Hamilton, ON L8N 3Z5, Canada
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 / John Wang / Dominique Besson
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  • World Health Organization, TDR, Special Programme for Research and Training for Neglected Disease, 20 Avenue Appia, 1211 Geneva, Switzerland
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 / Denis Crankshaw
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  • Department of Obstetrics and Gynecology, McMaster University, HSC 3N52, 1200 Main St. West, Hamilton, ON L8N 3Z5, Canada
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 / Günter Gauglitz
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  • Institut für Physikalische und Theoretische Chemie, Universität Tübingen, Auf der Morgenstelle 8, D-72076 Tübingen, Germany
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 / Robert Hertzberg
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  • GlaxoSmithKline Pharmaceuticals, 709 Swedeland Road, King of Prussia, PA 19406, USA
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 / Carol Homon / Lyndon Llewellyn
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  • Boehringer Ingelheim Pharmaceuticals, Inc., 900 Ridgebury Road, Ridgefield, CT 06877, USA
  • Australian Institute of Marine Science, PMB 3, Townsville 4810, Australia
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 / Richard Neubig
  • Corresponding author
  • Boehringer Ingelheim Pharmaceuticals, Inc., 900 Ridgebury Road, Ridgefield, CT 06877, USA
  • Department of Pharmacology, University of Michigan, Ann Arbor, MI 48109-1055, USA
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 / Larry Walker
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  • Boehringer Ingelheim Pharmaceuticals, Inc., 900 Ridgebury Road, Ridgefield, CT 06877, USA
  • National Center for Natural Products Research, The University of Mississippi, P.O. Box 1848, University, MS 38677, USA
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 / Pascal Villa
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  • Boehringer Ingelheim Pharmaceuticals, Inc., 900 Ridgebury Road, Ridgefield, CT 06877, USA
  • IFR 85 “Biomolécules et Innovations Thérapeutiques” 74 Route du Rhin BP 60024, 67401 Illkirch, France
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Published Online: 2011-02-07 | DOI: https://doi.org/10.1351/PAC-REC-09-05-03

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Biomolecular screening is now a crucial component of the drug discovery process, and this glossary will be of use to practitioners in the field of screening and to those who interact with the screening community. The glossary contains definitions related to various aspects of the screening process such as assay types, data handling, and relevant technologies. Many of the terms used in this discipline are not covered by existing glossaries, and where they are, the definitions are often not appropriate for this field. Where appropriate, this document provides new or modified definitions to better reflect the new context. The field of biomolecular screening is multidisciplinary in nature, and this glossary, containing authoritative definitions, will be useful not only for regular practitioners, but also for those who make use of data generated during the screening process.

Keywords: assay types; biomolecular screening; data handling; drug discovery; glossary; IUPAC Chemistry and Human Health Division

Project Year: 2004, Project Code: 2004-019-3-700

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About the article

Published Online: 2011-02-07

Published in Print: 2011-02-07

Citation Information: Pure and Applied Chemistry, Volume 83, Issue 5, Pages 1129–1158, ISSN (Online) 1365-3075, ISSN (Print) 0033-4545, DOI: https://doi.org/10.1351/PAC-REC-09-05-03.

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