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Prenatal Cardiology

Editor-in-Chief: Respondek-Liberska, Maria

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Assessment of the accuracy in prenatal diagnosis of congenital malformations. Analysis of 101 questionnaires filled in by parents of neonates hospitalized in the Department of Congenital Malformations Polish Mother's Memorial Research Institute

Iwona Strzelecka
  • Corresponding author
  • Medical University of Lodz, Department of Diagnoses and Prevention Fetal Malformations
  • Medical University of Lodz, Department of Embryology and Histology
  • Email
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Maciej Słodki
  • Department of Prenatal Cardiology, Polish Mother's Memorial Hospital Research Institute
  • Institute of Health Sciences. The State School of Higher Professional Education in Plock
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Andrzej Zieliński / Iwona Maroszyńska
  • Department of Intesive Therapy and Newborns' Malformations, Polish Mother's Memorial Hospital, Research Institute
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Maria Respondek-Liberska
  • Medical University of Lodz, Department of Diagnoses and Prevention Fetal Malformations
  • Department of Prenatal Cardiology, Polish Mother's Memorial Hospital Research Institute
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
Published Online: 2016-03-05 | DOI: https://doi.org/10.1515/pcard-2015-0003



Prenatal diagnosis is an integral part of modern perinatal care. In the article results of questionnaires pertaining to the prenatal process of diagnosis are presented. Parents whose children were afflicted with congenital malformations of all types responded to enquiry

Materials and methods:

Between March 2014 and March 2015 150 of 355 infants were hospitalized in the Department of Pediatric Intensive Care and Congenital Malformations in Łódź, and 150 had congenital malformations.


101 parents of 150 children (67,3%) have given the feedback. Anomalies were such as: of the digestive system (37%), CHD (25%), OUN (14 %), genito-urinary (13%), skeletal system (9%) and respiratory system (2%). In 65 children of 101 the defects were detected prenatally. The obstetric US exam was the most frequently pointed out as performed (more than 1200). The biochemical markers and genetic tests in were performed in 34 pregnancies. The high percentage of ability to detect malformation was reported in the group of fetal echo examinations.


1. Prenatal ultrasound exams were the least effective method of making appropriate prenatal diagnosis of congenital malformation.

2. Fetal echocardiography had a high level of sensitivity and specificity in detecting congenital malformations.

3. Prenatal cardiologists proved to be the most effective in detecting congenital malformations 89,3 % of detected abnormalities.

4. Biochemical exams had a positive result in only one case of Down Syndrome.

Keywords : prenatal diagnosis; congenital malformation; accuracy of diagnosis


  • 1. Respondek-Liberska M.: Prenatal cardiology, Czelej, Lublin 2006Google Scholar

  • 2. Perenc M.: Prenatal diagnoses of congenital malformations - invasive and noninvasive methods. Przew. Lek. 2002, 5, 5, 94-99Google Scholar

  • 3. Dangel J.:Prenatal diagnoses: myths and reality. Nauka 3/2007, 31-47Google Scholar

  • 4. Benoit RM, Copel JA. Antenatal screening with fetal echocardiography: when and how. Contemporary OB/GYN, Vol. 48, No 9, September 2003, p.59Google Scholar

  • 5. Eik-Nes S, Lee W, Carvalho JS, Chaoui R, Copel J, Hecher K, Paladini D. Cardiac creening examination of the fetus: guidelines for performing the ‘basic’ and ‘extended basic’ cardiac scan. ISUOG Guidelines Ultrasound Obstet Gynecol 2006; 27: 107-113Google Scholar

  • 6. Respondek-Liberska M.: Prenatal echocardiography and prenatal cardiology, Mak-Med, Gdańsk 1998Google Scholar

  • 7. Gembruch U. Prenatal diagnosis of congenital heart disease. Prenat Diagn. 1997 Dec;17:1283-98Google Scholar

  • 8. Respondek-Liberska M. Prenatal echocardiography in 1st,2nd and 3rd trimester in singelton pregnancy. Prenatal Cardiology 2012,2,6-11Google Scholar

  • 9. Respondek -Liberska M. Atlas wad serca u płodu. ADI 2011, 32.Google Scholar

  • 10. Wójtowicz A. Detection of fetal heart defects based on screening protocol of prenatal heart examination . Prenat Cardio 2012, 2, 11-16Google Scholar

  • 11. Sharony R, Fejgin MD, Biron-Shental T, Hershko-Klement A, Amiel A, Levi A.: Who should be offered fetal echocardiography? One center‘s experience with 3965 cases. Isr Med Assoc J. 2009, 11, 542-5Google Scholar

  • 12. Sharland G.: Fetal cardiac screening: why bother?. Arch Dis Child Fetal Neonatal Ed. 2010, 95:F64-8Google Scholar

  • 13. Wigton TR, Sabbagha RE, Tamura RK, Cohen L, Minogue JP, Strasburger JF.: Sonographic diagnosis of congenital heart disease: comparison between the four-chamber view and multiple cardiac views. Obstet Gynecol. 1993, 82,219-24Google Scholar

  • 14. Warrier D, Saraf R, Maheshwari S, Suresh P, Shah S.: Awareness of fetal echo in Indian scenario. Ann Pediatr Cardiol. 2012, 5, 156-9CrossrefGoogle Scholar

  • 15. Gottliebson WM, Border WL, Franklin CM, Meyer RA, Michelfelder EC.: Accuracy of fetal echocardiography: a cardiac segment-specific analysis. Ultrasound Obstet Gynecol. 2006, 28, 15-21CrossrefGoogle Scholar

  • 16. Abu-Rustum RS, Daou L, Abu-Rustum SE.: Role of ultrasonography in early gestation in the diagnosis of congenital heart defects. J Ultrasound Med. 2010, 29, 817-21Google Scholar

  • 17. Plesinac S, Terzic M, Stimec B, Plecas D.: Value of fetal echocardiography in diagnosis of congenital heart disease in a Serbian university hospital. Int J Fertil Womens Med. 2007, 52, 89-92Google Scholar

  • 18. Słodki M, Rychik J, Moszura T, Janiak K, Respondek-Liberska M.: Measurement of the great vessels in the mediastinum could help distinguish true from false-positive coarctation of the aorta in the third trimester. J Ultrasound Med. 2009, 28,1313-7Google Scholar

  • 19. Respondek-Liberska M, Sysa A, Gadzinowski J: Financial comparison of neonatal transportation: in utero, by ambulance and by air transportation. Ginekol. Pol. 2004, 75, 326- 331Google Scholar

  • 20. Chaoi R, Rake A, Heling KS. Aortic arch with four vessels: Aberrant right subclavian artery.Ultrasound Obstet Ginecol. 2008,31,115-117.CrossrefGoogle Scholar

  • 21. Allan LD, Crawford DC, Chita SK. Prenatal screening for congenital heart disease. British Medical Journal.1986, 292, 1717-1719.Google Scholar

  • 22. Carvalho JS, Allan LD, Chaoui R, et al; International Society of Ultrasound in Obstetrics and Gynecology. ISUOG Practice Guidelines (updated): sonographic screening examination of the fetal heart. Ultrasound Obstet Gynecol. 2013;41:348-359CrossrefGoogle Scholar

  • 23. Kemper AR, Mahle WT, Martin GR, et al. Strategies for implementing screening for critical congenital heart disease. Pediatrics. 2011;128(5). Available at: www.pediatrics.org/cgi/content/full/128/5/e1259Web of ScienceGoogle Scholar

  • 24. Rebecca F. Liberman, MPH, Kelly D. Getz, PhD,Angela E. Lin, Cathleen A. Higgins,Sepehr Sekhavat, Glenn R. Markenson and Marlene Anderka. Delayed Diagnosis of Critical Congenital Heart Defects: Trends and Associated Factors Pediatrics 2014;134;e373Web of ScienceGoogle Scholar

  • 25. Dawson AL, Cassell CH, Riehle-Colarusso T,et al. Factors associated with late detection of critical congenital heart disease in newborns. Pediatrics. 2013;132(3). Available at: www.pediatrics.org/cgi/content/full/132/3/e604Google Scholar

  • 26. Oster ME, Lee KA, Honein MA, RiehleColarusso T, Shin M, Correa A. Temporal trends in survival among infants with critical congenital heart defects. Pediatrics.2013;131(5). Available at: www.pediatrics.org/cgi/content/full/131/5/e1502Google Scholar

  • 27. L. R. Freud, A. Moon-Grady, M. C. Escobar-Diaz, N. L. Gotteiner, L. T. Young, D. B. McElhinney and W. Tworetzky: Low rate of prenatal diagnosis among neonates with critical aortic stenosis: insight into the natural history in uteroGoogle Scholar

  • 28. Respondek-Liberska M, Sklansky M, Wood D, Słodki M, Weiner S, Cuneo B, Huhta J, Gembruch U, Rizzo G, Sharland G, Achiron R, Pruetz J. Recommendations for fetal echocardiography in singleton pregnancy in 2015. Prenat Cardio 2015, 2, 28-34Google Scholar

  • 29. Chaoui R. Fetal echocardiography: state of the art of the state of the heart. Ultrasound Obstet Gynecol. 2001;17:277-84 CrossrefGoogle Scholar

About the article

Received: 2015-10-11

Accepted: 2015-10-20

Published Online: 2016-03-05

Published in Print: 2015-12-01

Citation Information: Prenatal Cardiology, Volume 5, Issue 4, Pages 19–25, ISSN (Online) 2353-8201, DOI: https://doi.org/10.1515/pcard-2015-0003.

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© 2016. This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License. BY-NC-ND 4.0

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