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Radiochimica Acta

International Journal for chemical aspects of nuclear science and technology

Editor-in-Chief: Qaim, Syed M.

IMPACT FACTOR 2017: 1.202

CiteScore 2017: 1.22

SCImago Journal Rank (SJR) 2017: 0.409
Source Normalized Impact per Paper (SNIP) 2017: 0.869

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Volume 100, Issue 8-9


Inorganic chemistry in nuclear imaging and radiotherapy: current and future directions

V. Carroll / D.W. Demoin / T.J. Hoffman
  • Chemistry, University of Missouri, Columbia, MO 65211, USA / Internal Medicine, University of Missouri, Columbia, MO 65211, USA / Harry S Truman Memorial Veterans Hospital, Columbia, MO 65211, USA
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/ S.S. Jurisson
Published Online: 2014-04-15 | DOI: https://doi.org/10.1524/ract.2012.1964


Radiometals play an important role in diagnostic and therapeutic radiopharmaceuticals. This field of radiochemistry is multidisciplinary, involving radiometal production, separation of the radiometal from its target, chelate design for complexing the radiometal in a biologically stable environment, specific targeting of the radiometal to its in vivo site, and nuclear imaging and/or radiotherapy applications of the resultant radiopharmaceutical. The critical importance of inorganic chemistry in the design and application of radiometal-containing imaging and therapy agents is described from a historical perspective to future directions.

Keywords: Radiometals; Bifunctional chelates; Specific targeting; Nuclear imaging; Radiotherapy

About the article

Published Online: 2014-04-15

Published in Print: 2012-08-01

Citation Information: Radiochimica Acta, Volume 100, Issue 8-9, Pages 653–667, ISSN (Online) 2193-3405, ISSN (Print) 0033-8230, DOI: https://doi.org/10.1524/ract.2012.1964.

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©2014 by Walter de Gruyter Berlin/Boston. This article is distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. BY-NC-ND 3.0

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