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Radiochimica Acta

International Journal for chemical aspects of nuclear science and technology

Editor-in-Chief: Qaim, Syed M.

12 Issues per year

IMPACT FACTOR 2017: 1.202

CiteScore 2017: 1.22

SCImago Journal Rank (SJR) 2017: 0.409
Source Normalized Impact per Paper (SNIP) 2017: 0.869

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Volume 100, Issue 8-9


The present and future of medical radionuclide production

S. M. Qaim
  • Institut für Neurowissenschaften und Medizin, INM-5: Nuklearchemie, Forschungszentrum Jülich GmbH, 52425 Jülich, Germany
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Published Online: 2014-04-15 | DOI: https://doi.org/10.1524/ract.2012.1966


Medical radionuclide production technology is well established. Both reactors and cyclotrons are utilized for production; the positron emitters, however, are produced exclusively using cyclotrons. A brief survey of the production methods of most commonly used diagnostic and therapeutic radionuclides is given. The emerging radionuclides are considered in more detail. They comprise novel positron emitters and therapeutic radionuclides emitting low-range electrons and α-particles. The possible alternative production routes of a few established radionuclides, like 68Ga and 99mTc, are discussed. The status of standardisation of production data of the commonly used as well as of some emerging radionuclides is briefly mentioned. Some notions on anticipated future trends in the production and application of radionuclides are considered.

Keywords: Reactor and cyclotron production of medical radionuclides; γ-ray emitters for SPECT; Positron emitters for PET; Corpuscular radiation emitters for internal radiotherapy; Low and intermediate energy nuclear reactions; Radionuclide generators; Future directions

About the article

Published Online: 2014-04-15

Published in Print: 2012-08-01

Citation Information: Radiochimica Acta, Volume 100, Issue 8-9, Pages 635–651, ISSN (Online) 2193-3405, ISSN (Print) 0033-8230, DOI: https://doi.org/10.1524/ract.2012.1966.

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©2014 by Walter de Gruyter Berlin/Boston. This article is distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. BY-NC-ND 3.0

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