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Reviews on Environmental Health

Editor-in-Chief: Carpenter, David O. / Sly, Peter

Editorial Board: Brugge, Doug / Edwards, John W. / Field, R.William / Garbisu, Carlos / Hales, Simon / Horowitz, Michal / Lawrence, Roderick / Maibach, H.I. / Shaw, Susan / Tao, Shu / Tchounwou, Paul B.

IMPACT FACTOR 2018: 1.616

CiteScore 2018: 1.69

SCImago Journal Rank (SJR) 2018: 0.508
Source Normalized Impact per Paper (SNIP) 2018: 0.664

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Volume 29, Issue 4


Beneficial effects of natural products on cells during ionizing radiation

Seyed Jalal Hosseinimehr
  • Corresponding author
  • Department of Radiopharmacy, Faculty of Pharmacy, Traditional and Complementary Medicine Research Center, Mazandaran University of Medical Sciences, Sari 48175-861, Iran
  • Email
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
Published Online: 2014-04-02 | DOI: https://doi.org/10.1515/reveh-2014-0037


Natural products like vegetables, fruits, and herbs are widely consumed by humans on a daily basis. These natural products have many biologic and pharmacologic properties. Ionizing radiation (IR) can interact with macromolecules like DNA, which induces serious side effects on cells and tissues. Natural products can directly scavenge free radicals produced by IR, and they can also activate or inhibit enzymes or proteins involved in the oxidative stress. Several natural products have dual biologic effects on normal and cancer cells during radiation and might be of interest for use in patients during radiotherapy. In this review, the effects of natural products on genotoxicity and cell death induced by IR were reviewed and some potentiated compounds were discussed.

Keywords: ionizing radiation; natural product; radioprotective; radiosensitive


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About the article

Corresponding author: Seyed Jalal Hosseinimehr, Department of Radiopharmacy, Faculty of Pharmacy, Traditional and Complementary Medicine Research Center, Mazandaran University of Medical Sciences, Sari 48175-861, Iran, Phone/Fax: +98-151-3543084, E-mail: ;

Received: 2014-02-03

Accepted: 2014-02-27

Published Online: 2014-04-02

Published in Print: 2014-12-06

Citation Information: Reviews on Environmental Health, Volume 29, Issue 4, Pages 341–353, ISSN (Online) 2191-0308, ISSN (Print) 0048-7554, DOI: https://doi.org/10.1515/reveh-2014-0037.

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