Jump to ContentJump to Main Navigation
Show Summary Details
More options …

Reviews on Environmental Health

Editor-in-Chief: Carpenter, David O. / Sly, Peter

Editorial Board: Brugge, Doug / Edwards, John W. / Field, R.William / Garbisu, Carlos / Hales, Simon / Horowitz, Michal / Lawrence, Roderick / Maibach, H.I. / Shaw, Susan / Tao, Shu / Tchounwou, Paul B.


IMPACT FACTOR 2017: 1.284

CiteScore 2017: 1.29

SCImago Journal Rank (SJR) 2017: 0.438
Source Normalized Impact per Paper (SNIP) 2017: 0.603

Online
ISSN
2191-0308
See all formats and pricing
More options …
Volume 31, Issue 1

Issues

Exposure assessment of lead from food and airborne dusts and biomonitoring in pregnant mothers, their fetus and siblings in Karachi, Pakistan and Shimotsuke, Japan

Fujio Kayama
  • Corresponding author
  • Department of Environmental and Preventive Medicine, Jichi Medical University, Shimono, Tochigi, Japan
  • Email
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Zafar Fatmi / Akihiko Ikegami
  • Department of Environmental and Preventive Medicine, Jichi Medical University, Shimono, Tochigi, Japan
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Atsuko Mizuno / Mayumi Ohtsu
  • Department of Environmental and Preventive Medicine, Jichi Medical University, Shimono, Tochigi, Japan
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Nathern Mise
  • Department of Environmental and Preventive Medicine, Jichi Medical University, Shimono, Tochigi, Japan
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Xiaoyi Cui
  • Department of Environmental and Preventive Medicine, Jichi Medical University, Shimono, Tochigi, Japan
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Masanori Ogawa
  • Department of Environmental and Preventive Medicine, Jichi Medical University, Shimono, Tochigi, Japan
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Takako Sakamoto
  • Department of Environmental and Preventive Medicine, Jichi Medical University, Shimono, Tochigi, Japan
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Yoshiko Nakagi / Takahiko Yoshida / Ambreen Sahito / Shahla Naeem / Kulsoom Ghias
  • Department of Biological and Biomedical Science, Aga Khan University, Karachi, Sindh, Pakistan
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Hina Zuberi
  • Department of Biological and Biomedical Science, Aga Khan University, Karachi, Sindh, Pakistan
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Kanwal Tariq
  • Department of Biological and Biomedical Science, Aga Khan University, Karachi, Sindh, Pakistan
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Yayoi Kobayashi / Keiko Nohara
Published Online: 2016-03-08 | DOI: https://doi.org/10.1515/reveh-2015-0046

Abstract

Aim: Exposure assessment of lead (Pb) and Arsenic (As) from food, water, and house dust intake were assessed among pregnant women, their children and fetuses in Pakistan and Japan, as well as their body burden of the metals in their blood.

Method: Fifty families which included a pregnant woman, a fetus and the 1–3-year-old siblings were recruited in Karachi and Khairpur in Pakistan, and Shimotsuke and Asahikawa in Japan, respectively. Their dietary exposure to Pb and As was measured in 3-day food duplicates and drinking water by ICP-MP. Pb in house dust and respirable dust was evaluated with an energy dispersive X-ray fluorescence spectrometry. Non-radioactive isotope Pb profiles of blood specimens will be compared with those of the exposure origins, such as food duplicates, respirable house dust, the soils nearby, and gasoline.

Results: Judging from the data collected and analyzed so far, contribution from dietary intake is highly correlated to higher body burden of Pb among Pakistani mothers. Additional data analyses will reveal the status of Pb and As body burden in Pakistani mothers, fetuses and their siblings, and causal sources of high body burden is delineated by Pb isotope profile analysis of different sources of Pb exposure.

Keywords: food; house dust; infants; lead; pregnant mothers

References

  • 1.

    Lanphear BP, Hornung R, Khoury J, Yolton K, Baghurst P, et al. Low-level environmental lead exposure and children’s intellectual function: an international pooled analysis. Environ Health Perspect 2005;113(7):894–9.CrossrefGoogle Scholar

  • 2.

    Bellinger DC. What is an adverse effect? A possible resolution of clinical and epidemiological perspectives on neurobehavioral toxicity. Environ Res 2004;95:394–405.CrossrefGoogle Scholar

  • 3.

    Domingo JL, Perelló G, Giné Bordonaba J. Dietary intake of metals by the population of tarragona county (Catalonia, Spain): results from a duplicate diet study. Biol Trace Elem Res 2012;146(3):420–5.Web of ScienceCrossrefGoogle Scholar

  • 4.

    Lanphear BP, Hornung R, Ho M, Howard CR, Eberly S, et al. Environmental lead exposure during early childhood. J Pediatr 2002;140(1):40–7.CrossrefGoogle Scholar

  • 5.

    Kapaj S, Peterson H, Liber K, Bhattacharya P. Human health effects from chronic arsenic poisoning – A review. J Environ Sci Health A Tox Hazard Subst Environ Eng 2006;41(10):2399–428.CrossrefGoogle Scholar

  • 6.

    Schuhmacher-Wolz U, Dieter HH, Klein D, Schneider K. Oral exposure to inorganic arsenic: evaluation of its carcinogenic and non-carcinogenic effects. Crit Rev Toxicol 2009;39(4):271–98.Web of ScienceCrossrefGoogle Scholar

  • 7.

    Kadir MM, Janjua NZ, Kristensen S, Fatmi Z, Sathiakumar N. Status of children’s blood lead levels in Pakistan: implications for research and policy. Public Health 2008;122(7):708–15.CrossrefWeb of ScienceGoogle Scholar

  • 8.

    Iqbal MP. Lead pollution – A risk factor for cardiovascular disease in Asian developing countries. Pak J Pharm Sci 2012;25(1):289–94.Google Scholar

  • 9.

    Fatmi Z, Abbasi IN, Ahmed M, Kazi A, Kayama F. Burden of skin lesions of arsenicosis at higher exposure through groundwater of taluka Gambat district Khairpur, Pakistan: a cross-sectional survey. Environ Geochem Health 2013;35(3):341–6.CrossrefWeb of ScienceGoogle Scholar

  • 10.

    Hedrick VE, Dietrich AM, Estabrooks PA, Savla J, Serrano E, et al. Dietary biomarkers: advances, limitations and future directions. Nutr J 2012;11:109–12.Web of ScienceCrossrefGoogle Scholar

  • 11.

    Schecter A, Päpke O, Harris TR, Tung KC, Musumba A, et al. Polybrominated diphenyl ether (PBDE) levels in an expanded market basket survey of U.S. food and estimated PBDE dietary intake by age and sex. Environ Health Perspect 2006;114(10):1515–20.CrossrefGoogle Scholar

  • 12.

    Zahir E, Naqvi IM, Mohi Uddin S. Market basket survey of selected metals in fruits from Karachi city (Pakistan). J Basic Appl Sci 2009;5(2):47–52.Google Scholar

  • 13.

    Rahbar MH, White F, Agboatwalla M, Hozhabri S, Luby S. Factors associated with elevated blood lead concentrations in children in Karachi, Pakistan. Bull World Health Organ 2002;80:769–75.Google Scholar

About the article

Corresponding author: Fujio Kayama, Department of Environmental and Preventive Medicine, Jichi Medical University, Shimono, Tochigi, Japan, E-mail:


Received: 2015-10-14

Accepted: 2015-10-14

Published Online: 2016-03-08

Published in Print: 2016-03-01


Citation Information: Reviews on Environmental Health, Volume 31, Issue 1, Pages 33–35, ISSN (Online) 2191-0308, ISSN (Print) 0048-7554, DOI: https://doi.org/10.1515/reveh-2015-0046.

Export Citation

©2016 by De Gruyter.Get Permission

Comments (0)

Please log in or register to comment.
Log in