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Reviews on Environmental Health

Editor-in-Chief: Carpenter, David O. / Sly, Peter

Editorial Board: Brugge, Doug / Edwards, John W. / Field, R.William / Garbisu, Carlos / Hales, Simon / Horowitz, Michal / Lawrence, Roderick / Maibach, H.I. / Shaw, Susan / Tao, Shu / Tchounwou, Paul B.


IMPACT FACTOR 2018: 1.616

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2191-0308
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Volume 32, Issue 4

Issues

Evaluation of the carcinogenic risks at the influence of POPs

Aiman Nazhmetdinova
  • Corresponding author
  • Scientific and Practical Centre for Sanitary and Epidemiological Expertise and Monitoring, Committee for Public Health Protection of the Ministry of Health, 84 Auezov, Almaty, Republic of Kazakhstan, Phone: +7 727 376 03 71
  • Email
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Adlet Kassymbayev
  • Scientific and Practical Centre for Sanitary and Epidemiological Expertise and Monitoring, Committee for Public Health Protection of the Ministry of Health, 84 Auezov, Almaty, Republic of Kazakhstan
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Altinay Chalginbayeva
  • Scientific and Practical Centre for Sanitary and Epidemiological Expertise and Monitoring, Committee for Public Health Protection of the Ministry of Health, 84 Auezov, Almaty, Republic of Kazakhstan
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
Published Online: 2017-08-30 | DOI: https://doi.org/10.1515/reveh-2017-0016

Abstract

Introduction:

Kazakhstan is included in the list of environmentally vulnerable countries and Kyzylorda oblast in particular. This is due to its geographical, spatial and temporal and socioeconomic features.

Materials and methods:

As part of the program “Integrated approaches in the management of public health in the Aral region”, we have carried out an expertise on many samples of natural environments and products. Samples were selected in accordance with sampling procedures according to regulatory documents by specialists of the Pesticide Toxicology Laboratory. It is accredited by the State Standard of the Republic of Kazakhstan, for compliance with ST RK ISO/IEC 17025-2007 “General requirements for the competence of test and calibration laboratories”. Gas chromatograph was used for the determination of residues of organochlorine pesticides. For the determination of dioxins, polychlorinated biphenyl was conducted on the gas chromatomass spectrometer with quadruple detector produce by Agilent Company, USA. To assess the risk, we carried out the mathematical calculations according to the risk of chemicals polluting (No P 2.1.10.1920-04, Russia). Calculation of the carcinogenic risk was carried out with the use of data on the size of the exposure and meanings of carcinogenic potential factors (slope factor and unit risk).

Results and discussion:

The evaluation of persistent organic pollutants (POPs), based on the previous results of the research concerning water, soil and food products, was held in five population settlements in Kyzylorda oblast villages: Ayteke bi, Zhalagash, Zhosaly, Shieli and Aralsk town. Pollution with the POPs in the environmental objects by means of exposition and evaluation of the carcinogenic risk to human health is confirmed by the data of the statistical reporting about some morbidity in Kyzylorda oblast, such as skin diseases and subcutaneous tissue, endocrine system diseases, pregnancy complications etc.

Conclusion:

The received levels of carcinogenic risks, which were first carried out in the Republic of Kazakhstan in the village of Shieli, meet the third-risk range, which is not acceptable to the life of the population that again shows the problem of the Aral Sea, called the zone of ecological disaster.

Keywords: carcinogenic risks; ecological diseases; natural environments; persistent organic pollutants

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About the article

Received: 2017-05-18

Accepted: 2017-07-04

Published Online: 2017-08-30

Published in Print: 2017-12-20


Author statement

Research funding: Authors state no funding involved. Conflict of interest: Authors state no conflict of interest. Informed consent: Informed consent is not applicable. Ethical approval: Samples were selected in accordance with sampling procedures according to regulatory documents by specialists of the Pesticide Toxicology Laboratory. It is accredited by the State Standard of the Republic of Kazakhstan, for compliance with ST RK ISO/IEC 17025-2007 “General requirements for the competence of test and calibration laboratories”.


Citation Information: Reviews on Environmental Health, Volume 32, Issue 4, Pages 373–378, ISSN (Online) 2191-0308, ISSN (Print) 0048-7554, DOI: https://doi.org/10.1515/reveh-2017-0016.

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