Statistical Applications in Genetics and Molecular Biology
Editor-in-Chief: Sanguinetti, Guido
IMPACT FACTOR 2018: 0.536
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Source Normalized Impact per Paper (SNIP) 2018: 0.342
Mathematical Citation Quotient (MCQ) 2018: 0.02
Statistical Inference in Evolutionary Models of DNA Sequences via the EM Algorithm
We describe statistical inference in continuous time Markov processes of DNA sequences related by a phylogenetic tree. The maximum likelihood estimator can be found by the expectation maximization (EM) algorithm and an expression for the information matrix is also derived. We provide explicit analytical solutions for the EM algorithm and information matrix.
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