This multifaceted essay emerges from a host of sources within diverse academic settings. Its central thesis is guided by physicist John A. Wheeler's thoughts on the quantum enigma. Wheeler concludes, following Niels Bohr, that we are co-participants within the universal self-organizing process. This notion merges with concepts from Peirce's process philosophy, Eastern thought, issues of topology, and border theory in cultural studies and social science, while surrounding itself with such key terms as complementarity, interdependence, interrelatedness, vagueness, generality, incompleteness, inconsistency, and mestizaje. Ultimately, a sense of semiosic process pervades in light of combined homogenous and hetergenous tendencies.