[1] Hakak Y., Walker J.R., Li C., Wong W.H., Davis K.L., Buxbaum J.D. et al., Genome-wide expression analysis reveals dysregulation of myelination-related genes in chronic schizophrenia, Proc Natl Acad Sci U S A, 2001; 98, 4746–4751 http://dx.doi.org/10.1073/pnas.081071198CrossrefGoogle Scholar
[2] Tkachev D., Mimmack M.L., Ryan M.M., Wayland M., Freeman T., Jones P.B. et al., Oligodendrocyte dysfunction in schizophrenia and bipolar disorder, Lancet, 2003; 362, 798–805 http://dx.doi.org/10.1016/S0140-6736(03)14289-4CrossrefGoogle Scholar
[3] Wan C., Yang Y., Feng G., Gu N., Liu H., Zhu S. et al., Polymorphisms of myelin-associated glycoprotein gene are associated with schizophrenia in the Chinese Han population, Neurosci Lett, 2005; 388, 126–131 Google Scholar
[4] Hof P.R., Haroutunian V., Friedrich V.L., Jr., Byne W., Buitron C., Perl D.P. et al., Loss and altered spatial distribution of oligodendrocytes in the superior frontal gyrus in schizophrenia, Biol Psychiatry, 2003; 53, 1075–1085 http://dx.doi.org/10.1016/S0006-3223(03)00237-3CrossrefGoogle Scholar
[5] Uranova N.A., Vostrikov V.M., Orlovskaya D.D., Rachmanova V.I., Oligodendroglial density in the prefrontal cortex in schizophrenia and mood disorders: a study from the Stanley Neuropathology Consortium, Schizophr Res, 2004; 67, 269–275 http://dx.doi.org/10.1016/S0920-9964(03)00181-6CrossrefGoogle Scholar
[6] Uranova N., Orlovskaya D., Vikhreva O., Zimina I., Kolomeets N., Vostrikov V. et al., Electron microscopy of oligodendroglia in severe mental illness, Brain Res Bull, 2001; 55, 597–610 http://dx.doi.org/10.1016/S0361-9230(01)00528-7CrossrefGoogle Scholar
[7] Arnone D., McIntosh A.M., Tan G.M., Ebmeier K.P., Meta-analysis of magnetic resonance imaging studies of the corpus callosum in schizophrenia, Schizophr Res, 2008, 101, 124–132 http://dx.doi.org/10.1016/j.schres.2008.01.005CrossrefGoogle Scholar
[8] Highley J.R., Esiri M.M., McDonald B., Cortina-Borja M., Herron B.M., Crow T.J., The size and fibre composition of the corpus callosum with respect to gender and schizophrenia: a post-mortem study, Brain, 1999; 122(Pt 1), 99–110 http://dx.doi.org/10.1093/brain/122.1.99CrossrefGoogle Scholar
[9] Buchsbaum M.S., Friedman J., Buchsbaum B.R., Chu K.W., Hazlett E.A., Newmark R. et al., Diffusion tensor imaging in schizophrenia, Biol Psychiatry, 2006; 60, 1181–1187 http://dx.doi.org/10.1016/j.biopsych.2005.11.028CrossrefGoogle Scholar
[10] Buchsbaum M.S., Tang C.Y., Peled S., Gudbjartsson H., Lu D., Hazlett E.A. et al., MRI white matter diffusion anisotropy and PET metabolic rate in schizophrenia, NeuroReport, 1998; 9, 425–430 http://dx.doi.org/10.1097/00001756-199802160-00013CrossrefGoogle Scholar
[11] Hoptman M.J., Ardekani B.A., Butler P.D., Nierenberg J., Javitt D.C., Lim K.O., DTI and impulsivity in schizophrenia: a first voxelwise correlational analysis, NeuroReport, 2004; 15, 2467–2470 http://dx.doi.org/10.1097/00001756-200411150-00007CrossrefGoogle Scholar
[12] Kubicki M., McCarley R., Westin C.F., Park H.J., Maier S., Kikinis R. et al., A review of diffusion tensor imaging studies in schizophrenia, J Psychiatr Res, 2007; 41, 15–30 http://dx.doi.org/10.1016/j.jpsychires.2005.05.005CrossrefGoogle Scholar
[13] Kubicki M., Park H., Westin C.F., Nestor P.G., Mulkern R.V., Maier S.E. et al., DTI and MTR abnormalities in schizophrenia: analysis of white matter integrity, Neuroimage, 2005; 26, 1109–1118 http://dx.doi.org/10.1016/j.neuroimage.2005.03.026CrossrefGoogle Scholar
[14] Lim K.O., Hedehus M., Moseley M., de Crespigny A., Sullivan E.V., Pfefferbaum A., Compromised white matter tract integrity in schizophrenia inferred from diffusion tensor imaging, Arch Gen Psychiatry, 1999; 56, 367–374 http://dx.doi.org/10.1001/archpsyc.56.4.367CrossrefGoogle Scholar
[15] Miyata J., Hirao K., Namiki C., Fukuyama H., Okada T., Miki Y. et al., Interfrontal commissural abnormality in schizophrenia: tractography-assisted callosal parcellation, Schizophr Res, 2007; 97, 236–241 http://dx.doi.org/10.1016/j.schres.2007.07.032CrossrefGoogle Scholar
[16] Shergill S.S., Kanaan R.A., Chitnis X.A., O’Daly O., Jones D.K., Frangou S. et al., A diffusion tensor imaging study of fasciculi in schizophrenia, Am J Psychiatry, 2007; 164, 467–473 http://dx.doi.org/10.1176/appi.ajp.164.3.467CrossrefGoogle Scholar
[17] Benes F.M., Emerging principles of altered neural circuitry in schizophrenia, Brain Res Rev, 2000; 31, 251–269 http://dx.doi.org/10.1016/S0165-0173(99)00041-7CrossrefGoogle Scholar
[18] Selemon L.D., Goldman-Rakic P.S., The reduced neuropil hypothesis: a circuit based model of schizophrenia, Biol Psychiatry, 1999; 45, 17–25 http://dx.doi.org/10.1016/S0006-3223(98)00281-9CrossrefGoogle Scholar
[19] Devinsky O., Morrell M.J., Vogt B.A., Contributions of anterior cingulate cortex to behaviour, Brain, 1995; 118(Pt 1), 279–306 http://dx.doi.org/10.1093/brain/118.1.279CrossrefGoogle Scholar
[20] Dracheva S., Davis K.L., Chin B., Woo D.A., Schmeidler J., Haroutunian V., Myelin-associated mRNA and protein expression deficits in the anterior cingulate cortex and hippocampus in elderly schizophrenia patients, Neurobiol Dis, 2006; 21, 531–540 http://dx.doi.org/10.1016/j.nbd.2005.08.012CrossrefGoogle Scholar
[21] Katsel P., Davis K.L., Haroutunian V., Variations in myelin and oligodendrocyte-related gene expression across multiple brain regions in schizophrenia: a gene ontology study, Schizophr Res, 2005; 79, 157–173 http://dx.doi.org/10.1016/j.schres.2005.06.007CrossrefGoogle Scholar
[22] McCullumsmith R.E., Gupta D., Beneyto M., Kreger E., Haroutunian V., Davis K.L. et al., Expression of transcripts for myelination-related genes in the anterior cingulate cortex in schizophrenia, Schizophr Res, 2007; 90, 15–27 http://dx.doi.org/10.1016/j.schres.2006.11.017CrossrefGoogle Scholar
[23] Stark A.K., Uylings H.B., Sanz-Arigita E., Pakkenberg B., Glial cell loss in the anterior cingulate cortex, a subregion of the prefrontal cortex, in subjects with schizophrenia, Am J Psychiatry, 2004; 161, 882–888 http://dx.doi.org/10.1176/appi.ajp.161.5.882CrossrefGoogle Scholar
[24] Yakovlev P.I., Locke S., Limbic nuclei of thalamus and connections of limbic cortex. III. Corticocortical connections of the anterior cingulate gyrus, the cingulum, and the subcallosal bundle in monkey, Arch Neurol, 1961; 5, 364–400 CrossrefGoogle Scholar
[25] Schmahmann J.D., Pandya D.N., Wang R., Dai G., D’Arceuil H.E., de Crespigny A.J. et al., Association fibre pathways of the brain: parallel observations from diffusion spectrum imaging and autoradiography, Brain, 2007; 130, 630–653 http://dx.doi.org/10.1093/brain/awl359CrossrefGoogle Scholar
[26] Kubicki M., Westin C.F., Nestor P.G., Wible C.G., Frumin M., Maier S.E. et al., Cingulate fasciculus integrity disruption in schizophrenia: a magnetic resonance diffusion tensor imaging study, Biol Psychiatry, 2003; 54, 1171–1180 http://dx.doi.org/10.1016/S0006-3223(03)00419-0CrossrefGoogle Scholar
[27] Sun Z., Wang F., Cui L., Breeze J., Du X., Wang X. et al., Abnormal anterior cingulum in patients with schizophrenia: a diffusion tensor imaging study, NeuroReport, 2003; 14, 1833–1836 http://dx.doi.org/10.1097/00001756-200310060-00015CrossrefGoogle Scholar
[28] Wang F., Sun Z., Cui L., Du X., Wang X., Zhang H. et al., Anterior cingulum abnormalities in male patients with schizophrenia determined through diffusion tensor imaging, Am J Psychiatry, 2004; 161, 573–575 http://dx.doi.org/10.1176/appi.ajp.161.3.573CrossrefGoogle Scholar
[29] Fujiwara H., Namiki C., Hirao K., Miyata J., Shimizu M., Fukuyama H. et al., Anterior and posterior cingulum abnormalities and their association with psychopathology in schizophrenia: a diffusion tensor imaging study, Schizophr Res, 2007; 95, 215–222 http://dx.doi.org/10.1016/j.schres.2007.05.044CrossrefGoogle Scholar
[30] Segal D., Haznedar M.M., Hazlett E.A., Entis J.J., Newmark R.E., Torosjan Y. et al., Diffusion tensor anisotropy in the cingulate gyrus in schizophrenia, Neuroimage, 2010; 50, 357–365 http://dx.doi.org/10.1016/j.neuroimage.2009.12.071CrossrefGoogle Scholar
[31] Kumra S., Ashtari M., Cervellione K.L., Henderson I., Kester H., Roofeh D. et al., White matter abnormalities in early-onset schizophrenia: a voxel-based diffusion tensor imaging study, J Am Acad Child Adolesc Psychiatry, 2005; 44, 934–941 http://dx.doi.org/10.1097/01.chi.0000170553.15798.94CrossrefGoogle Scholar
[32] White T., Cullen K., Rohrer L.M., Karatekin C., Luciana M., Schmidt M. et al., Limbic structures and networks in children and adolescents with schizophrenia, Schizophr Bull, 2008; 34, 18–29 http://dx.doi.org/10.1093/schbul/sbm110CrossrefGoogle Scholar
[33] Li C., Tropak M.B., Gerlai R., Clapoff S., Abramow-Newerly W., Trapp B. et al., Myelination in the absence of myelin-associated glycoprotein, Nature, 1994; 369, 747–750 http://dx.doi.org/10.1038/369747a0CrossrefGoogle Scholar
[34] Loers G., Aboul-Enein F., Bartsch U., Lassmann H., Schachner M., Comparison of myelin, axon, lipid, and immunopathology in the central nervous system of differentially myelin-compromised mutant mice: a morphological and biochemical study, Mol Cell Neurosci, 2004; 27, 175–189 http://dx.doi.org/10.1016/j.mcn.2004.06.006CrossrefGoogle Scholar
[35] Weiss M.D., Hammer J., Quarles R.H., Oligodendrocytes in aging mice lacking myelin-associated glycoprotein are dystrophic but not apoptotic, J Neurosci Res, 2000; 62, 772–780 http://dx.doi.org/10.1002/1097-4547(20001215)62:6<772::AID-JNR3>3.0.CO;2-XCrossrefGoogle Scholar
[36] Weiss M.D., Luciano C.A., Quarles R.H., Nerve conduction abnormalities in aging mice deficient for myelin-associated glycoprotein, Muscle Nerve, 2001; 24, 1380–1387 http://dx.doi.org/10.1002/mus.1159CrossrefGoogle Scholar
[37] Montag D., Giese K.P., Bartsch U., Martini R., Lang Y., Bluthmann H. et al., Mice deficient for the myelin-associated glycoprotein show subtle abnormalities in myelin, Neuron, 1994; 13, 229–246 http://dx.doi.org/10.1016/0896-6273(94)90472-3CrossrefGoogle Scholar
[38] Pan B., Fromholt S.E., Hess E.J., Crawford T.O., Griffin J.W., Sheikh K.A. et al., Myelin-associated glycoprotein and complementary axonal ligands, gangliosides, mediate axon stability in the CNS and PNS: neuropathology and behavioral deficits in single- and double-null mice, Exp Neurol, 2005; 195, 208–217 http://dx.doi.org/10.1016/j.expneurol.2005.04.017CrossrefGoogle Scholar
[39] Quarles R.H., A hypothesis about the relationship of myelinassociated glycoprotein’s function in myelinated axons to its capacity to inhibit neurite outgrowth, Neurochem Res, 2009; 34, 79–86 http://dx.doi.org/10.1007/s11064-008-9668-yCrossrefGoogle Scholar
[40] Hoistad M., Segal D., Takahashi N., Sakurai T., Buxbaum J.D., Hof P.R., Linking white and grey matter in schizophrenia: oligodendrocyte and neuron pathology in the prefrontal cortex, Front Neuroanat, 2009; 3, 9 http://dx.doi.org/10.3389/neuro.05.009.2009CrossrefGoogle Scholar
[41] Zhang J., van Zijl P.C., Mori S., Three-dimensional diffusion tensor magnetic resonance microimaging of adult mouse brain and hippocampus, Neuroimage, 2002; 15, 892–901 http://dx.doi.org/10.1006/nimg.2001.1012CrossrefGoogle Scholar
[42] Hof P.R., Young W.G., Bloom F.E., Belichenko P.V., Celio M.R. Comparative Cytoarchitectonic Atlas of the C57BL/6 and 129/Sv Mouse Brains. Amsterdam: Elsevier; 2000. Google Scholar
[43] Schmued L., Slikker W., Jr., Black-gold: a simple, high-resolution histochemical label for normal and pathological myelin in brain tissue sections, Brain Res, 1999; 837, 289–297 http://dx.doi.org/10.1016/S0006-8993(99)01624-8CrossrefGoogle Scholar
[44] Calhoun M.E., Mouton P.R., Length measurement: new developments in neurostereology and 3D imagery, J Chem Neuroanat, 2001; 21, 257–265 http://dx.doi.org/10.1016/S0891-0618(01)00093-XCrossrefGoogle Scholar
[45] Kreczmanski P., Schmidt-Kastner R., Heinsen H., Steinbusch H.W., Hof P.R., Schmitz C., Stereological studies of capillary length density in the frontal cortex of schizophrenics, Acta Neuropathol, 2005; 109, 510–518 http://dx.doi.org/10.1007/s00401-005-1003-yCrossrefGoogle Scholar
[46] Mouton P.R., Gokhale A.M., Ward N.L., West M.J., Stereological length estimation using spherical probes, J Microsc, 2002; 206, 54–64 http://dx.doi.org/10.1046/j.1365-2818.2002.01006.xCrossrefGoogle Scholar
[47] Schmitz C., Hof P.R., Design-based stereology in neuroscience, Neuroscience, 2005; 130, 813–831 http://dx.doi.org/10.1016/j.neuroscience.2004.08.050CrossrefGoogle Scholar
[48] Schmitz C., Grolms N., Hof P.R., Boehringer R., Glaser J., Korr H., Altered spatial arrangement of layer V pyramidal cells in the mouse brain following prenatal low-dose X-irradiation. A stereological study using a novel three-dimensional analysis method to estimate the nearest neighbor distance distributions of cells in thick sections, Cereb Cortex, 2002; 12, 954–960 http://dx.doi.org/10.1093/cercor/12.9.954CrossrefGoogle Scholar
[49] Davis K.L., Stewart D.G., Friedman J.I., Buchsbaum M., Harvey P.D., Hof P.R. et al., White matter changes in schizophrenia: evidence for myelin-related dysfunction, Arch Gen Psychiatry, 2003; 60, 443–456 http://dx.doi.org/10.1001/archpsyc.60.5.443CrossrefGoogle Scholar
[50] Kubicki M., McCarley R.W., Shenton M.E., Evidence for white matter abnormalities in schizophrenia, Curr Opin Psychiatry, 2005; 18, 121–134 http://dx.doi.org/10.1097/00001504-200503000-00004CrossrefGoogle Scholar
[51] Highley J.R., Esiri M.M., McDonald B., Roberts H.C., Walker M.A., Crow T.J., The size and fiber composition of the anterior commissure with respect to gender and schizophrenia, Biol Psychiatry, 1999; au]45, 1120–1127 http://dx.doi.org/10.1016/S0006-3223(98)00323-0CrossrefGoogle Scholar
[52] Chance S.A., Highley J.R., Esiri M.M., Crow T.J., Fiber content of the fornix in schizophrenia: lack of evidence for a primary limbic encephalopathy, Am J Psychiatry, 1999; 156, 1720–1724 Google Scholar
[53] Marner L., Pakkenberg B., Total length of nerve fibers in prefrontal and global white matter of chronic schizophrenics, J Psychiatr Res, 2003; 37, 539–547 http://dx.doi.org/10.1016/S0022-3956(03)00069-4CrossrefGoogle Scholar
[54] Highley J.R., Walker M.A., Esiri M.M., Crow T.J., Harrison P.J., Asymmetry of the uncinate fasciculus: a post-mortem study of normal subjects and patients with schizophrenia, Cereb Cortex, 2002; 12, 1218–1224 http://dx.doi.org/10.1093/cercor/12.11.1218CrossrefGoogle Scholar
[55] Casanova M.F., Zito M., Bigelow L.B., Berthot B., Sanders R.D., Kleinman J.E., Axonal counts of the corpus callosum of schizophrenic patients, J Neuropsychiatry Clin Neurosci, 1989; 1, 391–393 Google Scholar
[56] Nasrallah H.A., McCalley-Whitters M., Bigelow L.B., Rauscher F.P., A histological study of the corpus callosum in chronic schizophrenia, Psychiatry Res, 1983; 8, 251–260 http://dx.doi.org/10.1016/0165-1781(83)90013-6CrossrefGoogle Scholar
[57] Segal D., Schmitz C., Hof P.R., Spatial distribution and density of oligodendrocytes in the cingulum bundle are unaltered in schizophrenia, Acta Neuropathol, 2009; 117, 385–394 http://dx.doi.org/10.1007/s00401-008-0379-xCrossrefGoogle Scholar
[58] Peters A., The effects of normal aging on myelin and nerve fibers: a review, J Neurocytol, 2002; 31, 581–593 http://dx.doi.org/10.1023/A:1025731309829CrossrefGoogle Scholar
[59] Voineskos A.N., Lobaugh N.J., Bouix S., Rajji T.K., Miranda D., Kennedy J.L. et al., Diffusion tensor tractography findings in schizophrenia across the adult lifespan, Brain, 2010; 133, 1494–1504 http://dx.doi.org/10.1093/brain/awq040CrossrefGoogle Scholar
[60] Kaufman J.A., Ahrens E.T., Laidlaw D.H., Zhang S., Allman J.M., Anatomical analysis of an aye-aye brain (Daubentonia madagascariensis, Primates: Prosimii) combining histology, structural magnetic resonance imaging, and diffusion-tensor imaging, Anat Rec, 2005; 287A, 1026–1037 http://dx.doi.org/10.1002/ar.a.20264CrossrefGoogle Scholar
Comments (0)