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Zeitschrift für Naturforschung B

A Journal of Chemical Sciences

12 Issues per year


IMPACT FACTOR 2016: 0.631

SCImago Journal Rank (SJR) 2016: 0.237
Source Normalized Impact per Paper (SNIP) 2016: 0.332

Online
ISSN
1865-7117
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Volume 20, Issue 6

Issues

Kreuzreaktionen von Antiseren gegen heterologe terminale Aminosäuresequenzen und zwei Stämmen des Tabakmosaikvirus

F. Alfred Anderer / Horst-Dieter Schlumberger
Published Online: 2014-06-02 | DOI: https://doi.org/10.1515/znb-1965-0614

Artifical antigens with the peptides Pro-Ala-SerOH, Ala-Pro-Ala-ThrOH and Ser-Ala-Pro-Ala-ThrOH were prepared. The cross-reactivity and the neutralizing capacity of the corresponding antisera were tested with TMV-strain Vulgare and strain Dahlemense.

Antisera against homologous terminal sequences show the same neutralizing capacity for the virus as antisera against the intact virus. Structural changes of 1 — 2 Å units in the terminal residues of the haptenic groups of the artificial antigens diminish the neutralizing capacity of the corresponding antisera for the virus. Structural changes in non-terminal residues (the fourth position from the end) do not significantly diminish the neutralizing capacity of the corresponding antisera when tested with TMV-strain Vulgare and strain Dahlemense.

About the article

Received: 1965-01-28

Published Online: 2014-06-02

Published in Print: 1965-06-01


Citation Information: Zeitschrift für Naturforschung B, Volume 20, Issue 6, Pages 564–568, ISSN (Online) 1865-7117, ISSN (Print) 0932-0776, DOI: https://doi.org/10.1515/znb-1965-0614.

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© 1946 – 2014: Verlag der Zeitschrift für Naturforschung. This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License. BY-NC-ND 3.0

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