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Zeitschrift für Naturforschung B

A Journal of Chemical Sciences

12 Issues per year


IMPACT FACTOR 2016: 0.631

CiteScore 2017: 0.68

SCImago Journal Rank (SJR) 2017: 0.277
Source Normalized Impact per Paper (SNIP) 2017: 0.394

Online
ISSN
1865-7117
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Volume 21, Issue 3

Issues

Synthese und Umsatz von Ribonucleinsäuren in suspendierten Säugetierzellen

I. Einfluß der Stoffwechsellage

G. Koch
  • Heinrich-Pette-Institut für Experimentelle Virologie und Immunologie an der Universität Hamburg (Stiftung zur Erforschung der spinalen Kinderlähmung und der Multiplen Sklerose)
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ H. Kubinski
  • Heinrich-Pette-Institut für Experimentelle Virologie und Immunologie an der Universität Hamburg (Stiftung zur Erforschung der spinalen Kinderlähmung und der Multiplen Sklerose)
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ G. Trams
  • Heinrich-Pette-Institut für Experimentelle Virologie und Immunologie an der Universität Hamburg (Stiftung zur Erforschung der spinalen Kinderlähmung und der Multiplen Sklerose)
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
Published Online: 2014-06-02 | DOI: https://doi.org/10.1515/znb-1966-0311

Suspended tissue culture cells incorporate 32P within 60 -90 min. into two high molecular weight RNA fractions which can be separated by chromatography on methylated serum albumin celite columns. One fraction contains mainly ribosomal precursor RNA. the other ribosomal precursor RNA and cell messenger RNA. Under unfavorable growth conditions which do not allow cells to multiply the synthesis of ribosomal precursor RNA is inhibited and high molecular weight RNA accumulates which resembles cellular DNA in nucleotide composition. The experimental results indicate that the synthesis of ribosomal precursor RNA and of messenger RNA in mammalian cells are independently regulated.

About the article

Received: 1965-09-18

Published Online: 2014-06-02

Published in Print: 1966-03-01


Citation Information: Zeitschrift für Naturforschung B, Volume 21, Issue 3, Pages 261–266, ISSN (Online) 1865-7117, ISSN (Print) 0932-0776, DOI: https://doi.org/10.1515/znb-1966-0311.

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© 1946 – 2014: Verlag der Zeitschrift für Naturforschung. This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License. BY-NC-ND 3.0

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