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BY-NC-ND 3.0 license Open Access Published by De Gruyter June 2, 2014

Zur Reaktivität von C=N-Doppelbindungssystemen, XV [1] Die Reaktion von Anilinomethylen-barbitursäuren mit methylenaktiven Nitrilen / The Reactivity of the C=N-Double Bond System, XV [1] The Reaction of Anilinomethylene-barbituric Acids with Methylenactive Nitriles

  • Helmut Wipfler , Erich Ziegler and Otto S. Wolfbeis

N,N′-Dimethyl-5-anilinomethylene-barbituric acids and its thio analogues react with alkyl cyanoacetates or malodinitrile in DMF in the presence of KOH to give 1,2,3,4- Tetrahydro-7 H-pyrano[2,3-d]pyrimidines, whereas N-unsubstituted anilinomethylenebarbituric acids under the same conditiones afford 1,2,3,4-tetrahydro-pyrimidine-5-propenoic acid derivatives.

Received: 1976-5-26
Published Online: 2014-6-2
Published in Print: 1978-9-1

© 1946 – 2014: Verlag der Zeitschrift für Naturforschung

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

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