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Zeitschrift für Naturforschung B

A Journal of Chemical Sciences

12 Issues per year


IMPACT FACTOR 2016: 0.631

SCImago Journal Rank (SJR) 2016: 0.237
Source Normalized Impact per Paper (SNIP) 2016: 0.332

Online
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1865-7117
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Volume 43, Issue 5 (May 1988)

Issues

Nachweis von Corticosteroiden im Fett von Dachs und Murmeltier / Detection of Corticosteroids in Fat of Badger and of Alp-Marmot

H. Wagner
  • Institut für pharmazeutische Biologie der Ludwig-Maximilians-Universität München, 8 München 2, Karlstraße 29
/ D. Nusser
  • Institut für pharmazeutische Biologie der Ludwig-Maximilians-Universität München, 8 München 2, Karlstraße 29
Published Online: 2014-06-02 | DOI: https://doi.org/10.1515/znb-1988-0524

Abstract

In our search for the antiinflammatory activ principles of fat of badger and alp-marmot, used in folk-medicine as remedies against rheumatism and arthritis, eight known corticosteroids have been detected and identified in the lipophilic fraction of body fats of both animals. Enrichment and detection succeeded by using TLC, straight phase HPLC with diode array equipment, HR-GC on OV-1 capillary columns and GC/MS of the methyloxime-trimethylsilylated steroids. The amount of the detected steroids ranges from 30-40 mg/kg. The whole antiinflammatory activity of the fat, as measured in the rat paw edema test, results from these and further hitherto unidentified cortico-steroids.

Keywords: Fat; Badger; Alp-Marmot; Steroids; Corticosteroids

About the article

Received: 1988-01-07

Published Online: 2014-06-02

Published in Print: 1988-05-01


Citation Information: Zeitschrift für Naturforschung B, ISSN (Online) 1865-7117, ISSN (Print) 0932-0776, DOI: https://doi.org/10.1515/znb-1988-0524.

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© 1946 – 2014: Verlag der Zeitschrift für Naturforschung. This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License. BY-NC-ND 3.0

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