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Zeitschrift für Naturforschung B

A Journal of Chemical Sciences


IMPACT FACTOR 2018: 0.961

CiteScore 2018: 0.91

SCImago Journal Rank (SJR) 2018: 0.263
Source Normalized Impact per Paper (SNIP) 2018: 0.505

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1865-7117
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Volume 61, Issue 1

Issues

Niruriflavone, a New Antioxidant Flavone Sulfonic Acid from Phyllanthus niruri

N. N. Than / S. Fotso
  • Department of Organic and Biomolecular Chemistry, University of Göttingen, Tammannstraße 2, D-37077 Göttingen, Germany
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/ B. Poeggeler
  • Department of Zoology and Anthropology, University of Göttingen, Berliner Straße 28, D-37073 Göttingen, Germany
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/ R. Hardeland
  • Department of Zoology and Anthropology, University of Göttingen, Berliner Straße 28, D-37073 Göttingen, Germany
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/ H. Laatsch
  • Department of Organic and Biomolecular Chemistry, University of Göttingen, Tammannstraße 2, D-37077 Göttingen, Germany
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Published Online: 2014-06-02 | DOI: https://doi.org/10.1515/znb-2006-0111

A new flavone sulfonic acid 1 named niruriflavone was isolated from the 70% ethanolic extract of the whole plant of Phyllanthus niruri (Euphorbiaceae), together with 6,10,14-trimethyl-2- pentadecanone, hypophyllanthin, gallic acid, brevifolin carboxylic acid, methyl brevifolin carboxylate, isoquercetin, quercetin-3-O-β -D-glucopyranosyl(1→ 4)-α-rhamnopyranoside, corilagin, and isocorilagin, whose structures were determined by spectroscopic methods and comparison with published data. In an ABTS cation radical reduction assay, niruriflavone (1) exhibited potent radical scavenging properties. A biological test system based on bioluminescence of the dinoflagellate Lingulodinium polyedrum did not reveal any prooxidant properties of 1 at 50 μM.

Keywords: Phyllanthus niruri; Niruriflavone; Antioxidant Activity; Bioluminescent Dinoflagellates; Toxicity

About the article

Received: 2005-11-02

Published Online: 2014-06-02

Published in Print: 2006-01-01


Citation Information: Zeitschrift für Naturforschung B, Volume 61, Issue 1, Pages 57–60, ISSN (Online) 1865-7117, ISSN (Print) 0932-0776, DOI: https://doi.org/10.1515/znb-2006-0111.

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© 1946 – 2014: Verlag der Zeitschrift für Naturforschung. This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License. BY-NC-ND 3.0

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