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Zeitschrift für Naturforschung B

A Journal of Chemical Sciences

12 Issues per year


IMPACT FACTOR 2016: 0.631

CiteScore 2017: 0.68

SCImago Journal Rank (SJR) 2017: 0.277
Source Normalized Impact per Paper (SNIP) 2017: 0.394

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1865-7117
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Volume 62, Issue 8

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Synthesis of Some Ethyl 3-(Aryldiazenyl)-7-oxo-dihydropyrido[ 2,3-f]quinoxaline-8-carboxylates

Jalal A. Zahra / Monther A. Khanfar / Mustafa M. El-Abadelah / Bassam A. Abu Thaher / Naser S. El-Abadla / Wolfgang Voelter
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  • Interfakultäres Institut für Biochemie, Universität Tübingen, Hoppe-Seyler Str. 4, D-72076 Tübingen, Germany
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Published Online: 2014-06-02 | DOI: https://doi.org/10.1515/znb-2007-0807

Ethyl 7,8-diamino-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate (6) and its free acid 7 are prepared by chemical reduction of the respective 7-azido-8-nitroquinoline 5. Consecutive nucleophilic addition and cyclocondensation reactions of 6 with α-acetyl-N-arylhydrazonoyl chlorides 8a - c in ethanol and triethylamine are site-selective and yield the corresponding 3-(aryldiazinyl)- 2-methylpyrido[2,3- f ]quinoxalines 10a - c. Analytical and spectral (IR, MS, NMR) data of 6, 7, and 10a - c are in conformity with the assigned structures.

Keywords: 7,8-Diamino-4-oxoquinoline-3-carboxylate; α-Acetyl-N-arylhydrazonoyl Chlorides; Ethyl 7-Oxopyrido[2,3- f ]quinoxaline-8-carboxylates

About the article

Received: 2007-02-15

Published Online: 2014-06-02

Published in Print: 2007-08-01


Citation Information: Zeitschrift für Naturforschung B, Volume 62, Issue 8, Pages 1045–1051, ISSN (Online) 1865-7117, ISSN (Print) 0932-0776, DOI: https://doi.org/10.1515/znb-2007-0807.

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© 1946 – 2014: Verlag der Zeitschrift für Naturforschung. This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License. BY-NC-ND 3.0

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[2]
Jalal A. Zahra, Monther A. Khanfar, Mustafa M. El-Abadelah, Bassam A. Abu Thaher, Naser S. El-Abadla, and Wolfgang Voelter
ChemInform, 2007, Volume 38, Number 47

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