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Zeitschrift für Naturforschung B

A Journal of Chemical Sciences


IMPACT FACTOR 2017: 0.757

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1865-7117
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Volume 67, Issue 12

Issues

Two New Stilbenoids from Cajanus cajan

Nen-Ling Zhang
  • Key Laboratory of Plant Resources Conservation and Sustainable Utilization, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, P. R. China
  • Graduate University of Chinese Academy of Sciences, Beijing 100049, P. R. China
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Yue-Hui Zhu
  • Key Laboratory of Plant Resources Conservation and Sustainable Utilization, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, P. R. China
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Ri-Ming Huang
  • Key Laboratory of Plant Resources Conservation and Sustainable Utilization, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, P. R. China
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Man-Qin Fu
  • Key Laboratory of Plant Resources Conservation and Sustainable Utilization, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, P. R. China
  • Graduate University of Chinese Academy of Sciences, Beijing 100049, P. R. China
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Zhi-Wei Su
  • Key Laboratory of Plant Resources Conservation and Sustainable Utilization, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, P. R. China
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Jia-Zhong Cai / Ying-Jie Hu / Sheng-Xiang Qiu
  • Corresponding author
  • Key Laboratory of Plant Resources Conservation and Sustainable Utilization, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, P. R. China
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Published Online: 2014-06-02 | DOI: https://doi.org/10.5560/znb.2012-0184

Two new stilbenoids cajanotone and cajanamide A (1-2), together with another six known ones (3- 8) and four known dihydroflavones (9-12), have been isolated from the leaves of Cajanus cajan. Their structures were elucidated based on spectroscopic studies. A possible pathway to the new compounds 1 and 2 has been proposed. In vitro cytotoxicities of selected compounds against cancer cell lines HepG2, MCF-7 and A549 have been evaluated. Compounds 7 and 8 show strong cytotoxity against all the tested cell lines (with IC50 values in the range of 3.5 - 6.0 μM), and compounds 1 and 3 showed strong to moderate activity against the three cell lines.

Graphical Abstract

Two New Stilbenoids from Cajanus cajan

Two New Stilbenoids from Cajanus cajan

Keywords: Cajanus cajan; Pigeon Pea; Stilbenoid; Dihydroflavone; Cytotoxicity

About the article

Received: 2012-07-05

Published Online: 2014-06-02

Published in Print: 2012-12-01


Citation Information: Zeitschrift für Naturforschung B, Volume 67, Issue 12, Pages 1314–1318, ISSN (Online) 1865-7117, ISSN (Print) 0932-0776, DOI: https://doi.org/10.5560/znb.2012-0184.

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© 1946 – 2014: Verlag der Zeitschrift für Naturforschung. This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License. BY-NC-ND 3.0

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