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Zeitschrift für Naturforschung B

A Journal of Chemical Sciences

12 Issues per year


IMPACT FACTOR 2016: 0.631

SCImago Journal Rank (SJR) 2015: 0.279
Source Normalized Impact per Paper (SNIP) 2015: 0.379

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1865-7117
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Volume 68, Issue 10 (Oct 2013)

Issues

BIOnic Liquids: Imidazolium-based Ionic Liquids with Antimicrobial Activity

Frank Postleb
  • Universität zu Köln, Department für Chemie, Greinstr. 4, 50939 Köln, Germany
/ Danuta Stefanik
  • Universität zu Köln, Institut für Medizinische Mikrobiologie, Immunologie und Hygiene, Goldenfelsstr. 19 – 21, 50935 Köln, Germany
/ Harald Seifert
  • Universität zu Köln, Institut für Medizinische Mikrobiologie, Immunologie und Hygiene, Goldenfelsstr. 19 – 21, 50935 Köln, Germany
/ Ralf Giernoth
  • Corresponding author
  • Universität zu Köln, Department für Chemie, Greinstr. 4, 50939 Köln, Germany
  • Email:
Published Online: 2014-06-02 | DOI: https://doi.org/10.5560/znb.2013-3150

We have synthesized twelve new ionic liquids composed of an imidazolium-based cation in combination with an anion that shows antiobiotic or analgesic activity. These “BIOnic Liquids” have been tested towards their antibiotic activity in a standardized microbiological assay. A surprizingly large number of compounds shows high activity towards a set of bacteria which cannot be explained as simple cumulative effects. The general concept opens up completely new possibilities for the future development of pharmaceutically active compounds.

Graphical Abstract

BIOnic Liquids: Imidazolium-based Ionic Liquids with Antimicrobial Activity

Keywords: Ionic Liquids; Active Pharmaceutical Ingredients (API); Imidazolium Salts; Antibiotics; Antimicrobials; Analgesics

About the article

Received: 2013-06-07

Published Online: 2014-06-02

Published in Print: 2013-10-01



Citation Information: Zeitschrift für Naturforschung B, ISSN (Online) 1865-7117, ISSN (Print) 0932-0776, DOI: https://doi.org/10.5560/znb.2013-3150. Export Citation

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A. Reinhardt, M. Horn, J. Pieper gen. Schmauck, A. Bröhl, R. Giernoth, C. Oelkrug, A. Schubert, and I. Neundorf
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