Zeitschrift für Naturforschung B
A Journal of Chemical Sciences
IMPACT FACTOR 2015: 0.686
SCImago Journal Rank (SJR) 2015: 0.279
Source Normalized Impact per Paper (SNIP) 2015: 0.379
Impact per Publication (IPP) 2015: 0.606
BIOnic Liquids: Imidazolium-based Ionic Liquids with Antimicrobial Activity
1Universität zu Köln, Department für Chemie, Greinstr. 4, 50939 Köln, Germany
2Universität zu Köln, Institut für Medizinische Mikrobiologie, Immunologie und Hygiene, Goldenfelsstr. 19 – 21, 50935 Köln, Germany
Citation Information: Zeitschrift für Naturforschung B. Volume 68, Issue 10, Pages 1123–1128, ISSN (Online) 1865-7117, ISSN (Print) 0932-0776, DOI: 10.5560/znb.2013-3150, June 2014
- Published Online:
We have synthesized twelve new ionic liquids composed of an imidazolium-based cation in combination with an anion that shows antiobiotic or analgesic activity. These “BIOnic Liquids” have been tested towards their antibiotic activity in a standardized microbiological assay. A surprizingly large number of compounds shows high activity towards a set of bacteria which cannot be explained as simple cumulative effects. The general concept opens up completely new possibilities for the future development of pharmaceutically active compounds.
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