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Zeitschrift für Naturforschung B

A Journal of Chemical Sciences

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Volume 70, Issue 6

Issues

Taraxastane-type triterpene saponins isolated from Pittosporum angustifolium Lodd.

Christian Bäcker
  • Corresponding author
  • Institute of Pharmacy, Department of Pharmaceutical Biology, Ernst Moritz Arndt University Greifswald, Friedrich-Ludwig-Jahn-Straße 17, 17489 Greifswald, Germany
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  • Other articles by this author:
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/ Kristina Jenett-Siems
  • Institute of Pharmacy, Department of Pharmaceutical Biology, Free University of Berlin, Königin-Luise-Str. 2 + 4, 14195 Berlin, Germany
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/ Karsten Siems / Timo H.J. Niedermeyer
  • Interfaculty Institute of Microbiology and Infection Medicine, Eberhard Karls University Tübingen, Auf der Morgenstelle 28, 72076 Tübingen, Germany
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/ Martina Wurster
  • Institute of Pharmacy, Department of Pharmaceutical Biology, Ernst Moritz Arndt University Greifswald, Friedrich-Ludwig-Jahn-Straße 17, 17489 Greifswald, Germany
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/ Anja Bodtke
  • Institute of Pharmacy, Department of Pharmaceutical/Medicinal Chemistry, Ernst Moritz Arndt University Greifswald, Friedrich-Ludwig-Jahn-Straße 17, 17489 Greifswald, Germany
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/ Ulrike Lindequist
  • Institute of Pharmacy, Department of Pharmaceutical Biology, Ernst Moritz Arndt University Greifswald, Friedrich-Ludwig-Jahn-Straße 17, 17489 Greifswald, Germany
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Published Online: 2015-05-09 | DOI: https://doi.org/10.1515/znb-2015-0005

Abstract

Two new taraxastane-type triterpene saponins, named pittangretosides L (1) and C1 (2), were isolated from the leaves of Pittosporum angustifolium Lodd. Their structures were established by NMR spectroscopic, mass spectrometric and chemical means. The in vitro cytotoxicity was evaluated against four cell lines. The compounds exhibited no cytotoxic activity up to a concentration of 130 μm.

This article offers supplementary material which is provided at the end of the article.

Keywords: Pittosporaceae; Pittosporum angustifolium; taraxastane; triterpene saponins

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About the article

Corresponding author: Christian Bäcker, Institute of Pharmacy, Department of Pharmaceutical Biology, Ernst Moritz Arndt University Greifswald, Friedrich-Ludwig-Jahn-Straße 17, 17489 Greifswald, Germany, Fax: +49(0)3834864885, E-mail:


Received: 2015-01-07

Accepted: 2015-02-05

Published Online: 2015-05-09

Published in Print: 2015-06-01


Citation Information: Zeitschrift für Naturforschung B, Volume 70, Issue 6, Pages 403–408, ISSN (Online) 1865-7117, ISSN (Print) 0932-0776, DOI: https://doi.org/10.1515/znb-2015-0005.

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[1]
Christian Bäcker, Malgorzata N. Drwal, Robert Preissner, and Ulrike Lindequist
Natural Products and Bioprospecting, 2016, Volume 6, Number 2, Page 141

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