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Zeitschrift für Naturforschung B

A Journal of Chemical Sciences

IMPACT FACTOR 2018: 0.961

CiteScore 2018: 0.91

SCImago Journal Rank (SJR) 2018: 0.263
Source Normalized Impact per Paper (SNIP) 2018: 0.505

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Volume 72, Issue 10


Efficient synthesis of novel β-sitosterol scaffolds containing 1,2,3-triazole via copper(I)-catalyzed click reaction under microwave irradiation

Jin-Wei Yuan
  • Corresponding author
  • School of Chemistry and Chemical Engineering, Henan University of Technology; Academician Workstation for Natural Medical Chemistry of Henan Province, Zhengzhou 450001, P.R. China, Fax: +86 371 67756718
  • Email
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Ling-Bo Qu
  • School of Chemistry and Chemical Engineering, Henan University of Technology; Academician Workstation for Natural Medical Chemistry of Henan Province, Zhengzhou 450001, P.R. China
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
Published Online: 2017-09-22 | DOI: https://doi.org/10.1515/znb-2017-0074


In this work, new derivatives of the β-sitosterol scaffolds containing 1,2,3-triazole are prepared by the reaction of β-sitosterol with aromatic alkynes via copper(I)-catalyzed azide-alkyne cycloaddition reactions under microwave irradiation. The reaction has several advantages including high yields, short reaction times, and a simple work-up procedure.

This article offers supplementary material which is provided at the end of the article.

Keywords: click reaction; Cu(I)-catalyzed; β-sitosterol; steroid; 1,2,3-triazole


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About the article

Received: 2017-05-11

Accepted: 2017-07-05

Published Online: 2017-09-22

Published in Print: 2017-09-26

Citation Information: Zeitschrift für Naturforschung B, Volume 72, Issue 10, Pages 717–724, ISSN (Online) 1865-7117, ISSN (Print) 0932-0776, DOI: https://doi.org/10.1515/znb-2017-0074.

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