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Zeitschrift für Naturforschung B

A Journal of Chemical Sciences

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1865-7117
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Volume 73, Issue 6

Issues

Two new alkylresorcinol derivatives from the leaves of Scyphocephalium ochocoa

Hibrahim Foundikou
  • Department of Chemistry, Faculty of Science, Université des Sciences et Techniques de Masuku, Box. 943, Franceville, Gabon
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/ Marius Mbiantcha
  • Department of Animal Biology, Faculty of Sciences, University of Dschang, Box. 67, Dschang, Cameroon
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/ Jean-jules Bankeu Kezetas
  • Department of Chemistry, Faculty of Science, University of Bamenda, Box. 39, Bambili, Cameroon
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/ Jean Claude Tchouankeu
  • Department of Organic Chemistry, Faculty of Science, University of Yaoundé 1, Box. 812, Yaoundé, Cameroon
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/ Farzana Shaheen
  • International Center for Chemical and Biological Sciences, H.E.J. Research Institute of Chemistry, University of Karachi, Karachi-75270, Pakistan
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/ Muhammad Iqbal Choudhary
  • International Center for Chemical and Biological Sciences, H.E.J. Research Institute of Chemistry, University of Karachi, Karachi-75270, Pakistan
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/ Jacques Lebibi
  • Department of Chemistry, Faculty of Science, Université des Sciences et Techniques de Masuku, Box. 943, Franceville, Gabon
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/ Guy Raymond Feuya Tchouya
  • Corresponding author
  • Department of Chemistry, Faculty of Science, Université des Sciences et Techniques de Masuku, Box. 943, Franceville, Gabon, Tel.: +241 06043682/07622381, Fax: +241 01677578
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Published Online: 2018-05-29 | DOI: https://doi.org/10.1515/znb-2018-0008

Abstract

Two new alkylresorcinol derivatives, namely ochocinone A and ochocinone B (1, 2), as well as a known alkylresorcinol oleiferinone (3) were isolated from the methanol extract of the leaves of Scyphocephalium ochocoa. The structures of these compounds were established by detailed spectroscopic analysis and by comparison with the spectral data of related known compounds. Compounds 1–3 showed significant immunomodulatory activity and cytotoxic effect on the mammary carcinoma MCF-7 cell line.

This article offers supplementary material which is provided at the end of the article.

Keywords: cytotoxic activity; immunomodulatory activity; ochocinone A; ochocinone B; Scyphocephalium ochocoa

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About the article

Received: 2018-01-07

Accepted: 2018-04-21

Published Online: 2018-05-29

Published in Print: 2018-06-27


Competing interests: The authors declare that they have no competing interests.


Citation Information: Zeitschrift für Naturforschung B, Volume 73, Issue 6, Pages 381–388, ISSN (Online) 1865-7117, ISSN (Print) 0932-0776, DOI: https://doi.org/10.1515/znb-2018-0008.

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