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Zeitschrift für Naturforschung B

A Journal of Chemical Sciences

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Volume 73, Issue 7


Iminiumsalz-Strukturen bei der durch Pyridoxalphosphat (Vitamin B6) katalysierten Bildung von Aromastoffen und Fehlaromen im Wein

Iminium salt structures in the pyridoxal phosphate (vitamin B6) catalyzed formation of aroma compounds and off-odors in wine

Nikolaus Müller
Published Online: 2018-06-05 | DOI: https://doi.org/10.1515/znb-2018-0038


Enzymes that use pyridoxal phosphate (PLP, Vitamin B6) as cofactor constitute a ubiquitous class of biocatalysts. A variety of PLP-dependant enzymes mainly involved in biochemical pathways concerning amino acid metabolism are found in all forms of life. These enzymes also play an important role in wine production, as well in grape growing as in enological processes. The formation of pleasant aroma compounds often runs with participation of pyridoxal-dependant enzymes. But these are also brought into context with the formation of off-odors, especially from sulfur compounds (i.e. sulfur containing amino acids cysteine, methionine). The versatility of PLP-dependant bioreactions arises from its ability to covalently bind the substrate and then to function as an electrophilic catalyst, thereby stabilizing different types of carbanionic reaction intermediates, containing iminium salt structures. This article summarizes the influence of PLP on sensorically important aroma compounds in wine growing and wine processing.

Keywords: off-odors; pyridoxal phosphate; sulfur metabolism in wine making processes; wine aroma


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About the article

Received: 2018-02-24

Accepted: 2018-04-22

Published Online: 2018-06-05

Published in Print: 2018-07-26

Citation Information: Zeitschrift für Naturforschung B, Volume 73, Issue 7, Pages 521–533, ISSN (Online) 1865-7117, ISSN (Print) 0932-0776, DOI: https://doi.org/10.1515/znb-2018-0038.

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