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Zeitschrift für Naturforschung B

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Bis-heterocycles. Part I: tetrahydro-5,5′- bi(1,2,4-triazin-6-ones)

Hanan H. Mohammad / Mustafa M. El-Abadelah / Salim S. Sabri / Firas F. Awwadi / Wolfgang Voelter
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  • Interfakultäres Institut für Biochemie, Universität Tübingen, Hoppe-Seyler Straße 4, Tübingen 72076, Germany
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Published Online: 2018-11-09 | DOI: https://doi.org/10.1515/znb-2018-0148


Selected sets of tetrahydro-5,5′-bi(1,2,4-triazines) (1–3) appended with acetyl, benzoyl, and ester moieties at C-3 position and N-1 (p-substituted)phenyl ring have been prepared and characterized by spectral (IR, NMR, MS) data and X-ray diffraction for compound 3a. Their synthesis was achieved in high yield via the reaction of diethyl aminomalonate with various N-(aryl)hydrazonoyl chlorides in the presence of triethylamine.

This article offers supplementary material which is provided at the end of the article.

Keywords: diethyl aminomalonate; dihydro-1,2,4-triazin-6-ones; hydrazonoyl chlorides; oxidative dimerization; X-ray crystal structure


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About the article

Received: 2018-07-12

Accepted: 2018-08-31

Published Online: 2018-11-09

Citation Information: Zeitschrift für Naturforschung B, 20180148, ISSN (Online) 1865-7117, ISSN (Print) 0932-0776, DOI: https://doi.org/10.1515/znb-2018-0148.

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