Skip to content
BY-NC-ND 3.0 license Open Access Published by De Gruyter June 2, 2014

Synthesis and Bleaching Activity of 1-Ethyl-and 1 -Propy 1-5-Substituted Imidazoles

  • Naotaka Yamada , Eiichi Kuwano and Eto

Abstract

Twenty-eight 1-ethyl-and 1-propyl-5 -substituted imidazoles were synthesized an d their bleaching activity was evaluated by using the lettuce seedling test. 5-Phenyl-1-propylim idazole (1) caused distinct chlorosis, while none of the c ompounds with various alkenyl groups at the 5-position o the imidazole ring show ed this bleaching activity. Introduction of a bromo, chloro, fluoro, methyl or trifluoromethyl groupa t the 4-position on the benzene ring of com­pound 1 increased the activity in comparison with that of compound 1. 5-[4-(3-Chlorobenzyl-oxy)phenyl]-l-ethylimidazole (15) an d l-ethyl-5-[4-(3-methylbenzyloxy)phenyl]imidazole (21), analogs with a large substituent at the 4 -position on the benzene ring, also caused pronounced chlorosis in the lettuce seedlings. Both compounds 1 and 15 a t 30 ppm decreased total c arot­enoid content in the lettuce seedlings to less than 40% of that in the control, and the reduction of total carotenoid content correlated well with treatment dose.

Received: 1995-11-5
Published Online: 2014-6-2
Published in Print: 1993-4-1

© 1946 – 2014: Verlag der Zeitschrift für Naturforschung

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Downloaded on 29.3.2024 from https://www.degruyter.com/document/doi/10.1515/znc-1993-3-430/html
Scroll to top button