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BY-NC-ND 3.0 license Open Access Published by De Gruyter June 2, 2014

High-Gradient Magnetic Capture of Ferrofluids: Implications for Drug Targeting and Tumor Embolization

  • Melánia Babincová EMAIL logo , Peter Babinec and Christian Bergemann

Abstract

One of the perspective methods of cancer chemotherapy is magnetic targeting of drugs to tumors. This task is usually accomplished using small permanent magnets attached near the desired sites. In this study a new much more effective approach is proposed which is based on a strong magnetic gradient using a ferromagnetic wire placed in a strong magnetic field. Feasibility of this approach has been evaluated by the formation of ferrofluid seals and measurement of maximum pressure the formed seal can resists. Using this method it is possible to capture even superparamagnetic particles with nanos­ize dimensions, therefore the method may have an interesting applications in biomedical sciences.

Received: 2001-5-28
Revised: 2001-7-16
Published Online: 2014-6-2
Published in Print: 2001-10-1

© 1946 – 2014: Verlag der Zeitschrift für Naturforschung

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

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