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Zeitschrift für Naturforschung C

A Journal of Biosciences

Editor-in-Chief: Seibel, Jürgen

Editorial Board: Aigner , Achim / Boland, Wilhelm / Bornscheuer, Uwe / Hoffmann, Klaus


IMPACT FACTOR 2017: 0.882
5-year IMPACT FACTOR: 0.912

CiteScore 2017: 0.92

SCImago Journal Rank (SJR) 2017: 0.288
Source Normalized Impact per Paper (SNIP) 2017: 0.448

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1865-7125
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Volume 65, Issue 9-10

Issues

Antibacterial Activity of the Essential Oil from Rosmarinus offi cinalis and its Major Components against Oral Pathogens

Wagner A. Bernardes
  • Universidade de Franca, Av. Dr. Armando Salles de Oliveira, 201 Parque Universitário, Franca-SP, CEP 14404-600, Brazil
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/ Rodrigo Lucarini
  • Universidade de Franca, Av. Dr. Armando Salles de Oliveira, 201 Parque Universitário, Franca-SP, CEP 14404-600, Brazil
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/ Marcos G. Tozatti
  • Universidade de Franca, Av. Dr. Armando Salles de Oliveira, 201 Parque Universitário, Franca-SP, CEP 14404-600, Brazil
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/ Lúzio G. Bocalon Flauzino
  • Universidade de Franca, Av. Dr. Armando Salles de Oliveira, 201 Parque Universitário, Franca-SP, CEP 14404-600, Brazil
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/ Maria G. M. Souza
  • Universidade de Franca, Av. Dr. Armando Salles de Oliveira, 201 Parque Universitário, Franca-SP, CEP 14404-600, Brazil
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/ Isabel C. C. Turatti
  • Departamento de Física e Química da Faculdade de Ciências Farmacêuticas de Ribeirão Preto – USP, Av. do Café s/n, Ribeirão Preto-SP, CEP 14040-903, Brazil
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/ Marcio L. Andrade e Silva
  • Universidade de Franca, Av. Dr. Armando Salles de Oliveira, 201 Parque Universitario, Franca-SP, CEP 14404-600, Brazil
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/ Carlos H. G. Martins
  • Universidade de Franca, Av. Dr. Armando Salles de Oliveira, 201 Parque Universitário, Franca-SP, CEP 14404-600, Brazil
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/ Ademar A. da Silva Filho
  • Universidade de Franca, Av. Dr. Armando Salles de Oliveira, 201 Parque Universitário, Franca-SP, CEP 14404-600, Brazil
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/ Wilson R. Cunha
  • Corresponding author
  • Universidade de Franca, Av. Dr. Armando Salles de Oliveira, 201 Parque Universitário, Franca-SP, CEP 14404-600, Brazil
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Published Online: 2014-06-02 | DOI: https://doi.org/10.1515/znc-2010-9-1009

The essential oil of Rosmarinus officinalis L. (rosemary) was obtained by hydro-distillation and analysed by gas chromatography-mass spectrometry. Sixty-two constituents were identified, representing 98.06% of the total oil content. Oxygenated monoterpenes were the predominant components. The rosemary oil was characterized as having prominent (> 5%) contents of camphor (18.9%), verbenone (11.3%), α-pinene (9.6%), β-myrcene (8.6%), 1,8-cineole (8.0%), and β-caryophyllene (5.1%). The antimicrobial activity of the oil as well as of its major constituents was tested against the following microorganisms: Streptococcus mutans, Streptococcus mitis, Streptococcus sanguinis, Streptococcus salivarius, Streptococcus sobrinus, and Enterococcus faecalis, which are potentially responsible for the formation of dental caries in humans. The microdilution method was used for determination of the minimum inhibitory concentration (MIC) during evaluation of the antibacterial activity. The essential oil displayed low activity against the selected microorganisms. In the present study, the pure major compounds were more active than the essential oil. Among all the microorganisms tested, the pathogen S. mitis was the most susceptible and E. faecalis was the most resistant to the evaluated samples. This is the first report on antimicrobial activity of the major components of rosemary oil against oral pathogens.

Keywords: Rosmarinus officinalis; Antibacterial Activity; Oral Pathogens

About the article

Received: 2010-03-10

Revised: 2010-05-19

Published Online: 2014-06-02

Published in Print: 2010-10-01


Citation Information: Zeitschrift für Naturforschung C, Volume 65, Issue 9-10, Pages 588–593, ISSN (Online) 1865-7125, ISSN (Print) 0939-5075, DOI: https://doi.org/10.1515/znc-2010-9-1009.

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© 1946 – 2014: Verlag der Zeitschrift für Naturforschung. This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License. BY-NC-ND 3.0

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