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Zeitschrift für Naturforschung C

A Journal of Biosciences

Editor-in-Chief: Seibel, Jürgen

Editorial Board: Aigner , Achim / Boland, Wilhelm / Bornscheuer, Uwe / Hoffmann, Klaus

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1865-7125
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Volume 70, Issue 1-2

Issues

Synthesis and antimicrobial properties of N-substituted derivatives of (E)-2′,3″-thiazachalcones

Asu Usta
  • Corresponding author
  • Faculty of Arts and Sciences, Department of Chemistry, Recep Tayyip Erdogan University, 53100 Rize, Turkey
  • Email
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Hacer Taşkıran
  • Faculty of Arts and Sciences, Department of Biology, Recep Tayyip Erdogan University, 53100 Rize, Turkey
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
Published Online: 2015-03-27 | DOI: https://doi.org/10.1515/znc-2014-4182

Abstract

N-alkyl substituted 2′,3″-thiazachalcones {3-[(1E)-3-(4-methylthiophene-2-yl)-3-oxoprop-1-en-1-yl]-1-alkyl (C5–12,14) pyridinium bromides} were synthesized by a two-step reaction. The newly synthesized compounds were characterized by IR, 1H NMR, 13C NMR, elemental analysis and mass spectral studies. The synthesized compounds were tested for antibacterial activities and found to be more active against Gram-positive as compared to Gram-negative bacteria.

Keywords: antimicrobial activity; azachalcone; N-alkyl azachalconium bromide

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About the article

Corresponding author: Asu Usta, Faculty of Arts and Sciences, Department of Chemistry, Recep Tayyip Erdogan University, 53100 Rize, Turkey, Tel.: +90-464-2236126 Fax: +90-464-2234019, (office), E-mail:


Received: 2014-10-16

Revised: 2015-02-27

Accepted: 2015-03-04

Published Online: 2015-03-27

Published in Print: 2015-01-01


Citation Information: Zeitschrift für Naturforschung C, Volume 70, Issue 1-2, Pages 45–50, ISSN (Online) 1865-7125, ISSN (Print) 0939-5075, DOI: https://doi.org/10.1515/znc-2014-4182.

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