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Zeitschrift für Naturforschung C

A Journal of Biosciences

Editor-in-Chief: Seibel, Jürgen

Editorial Board: Aigner , Achim / Boland, Wilhelm / Bornscheuer, Uwe / Hoffmann, Klaus

IMPACT FACTOR 2018: 1.000

CiteScore 2018: 0.99

SCImago Journal Rank (SJR) 2018: 0.246
Source Normalized Impact per Paper (SNIP) 2018: 0.437

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Volume 73, Issue 9-10


Evaluation of Lavandula stoechas L. subsp. stoechas L., Mentha spicata L. subsp. spicata L. essential oils and their main components against sinusitis pathogens

Nursenem Karaca
  • Department of Pharmacognosy, Graduate School of Health Sciences, Anadolu University, Eskişehir, Turkey
  • Other articles by this author:
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/ Betül Demirci / Fatih Demirci
  • Corresponding author
  • Department of Pharmacognosy, Faculty of Pharmacy, Anadolu University, 26470-Eskişehir, Turkey, Phone: +90 (222) 335 05 80 – ext. 3711, Fax: +90 (222) 335 07 50, E-mail:
  • Email
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
Published Online: 2018-02-27 | DOI: https://doi.org/10.1515/znc-2017-0150


Lavandula stoechas subsp. stoechas and Mentha spicata subsp. spicata are used for the treatment of sinusitis in Turkish folk medicine. The components of essential oils obtained by hydrodistillation were determined by gas chromatography-flame ionization detector (GC-FID), gas chromatography/mass spectrometry (GC/MS), and thin layer chromatography (TLC). Major components of L. stoechas and M. spicata oils were determined as camphor (46.7%) and carvone (60.6%), respectively. The antibacterial activity of essential oils and their main components were tested against the common selected sinusitis pathogens Streptococcus pneumoniae, Streptococcus pyogenes, Staphylococcus aureus, Haemophilus influenzae, Moraxella catarrhalis, and Pseudomonas aeruginosa using in vitro agar diffusion, microdilution, and vapor diffusion methods. As a result, the tested plant materials, which are locally and natively used against sinusitis, were relatively mild antibacterial (in vitro MICs 310–1250 μg/mL) in action. To use essential oils and their components safely in sinusitis therapy, further detailed in vivo experiments are needed to support their efficacy.

This article offers supplementary material which is provided at the end of the article.

Keywords: antimicrobial activity; camphor; carvone; essential oils; sinusitis


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About the article

Received: 2017-08-22

Revised: 2017-12-15

Accepted: 2018-01-10

Published Online: 2018-02-27

Published in Print: 2018-09-25

Citation Information: Zeitschrift für Naturforschung C, Volume 73, Issue 9-10, Pages 353–360, ISSN (Online) 1865-7125, ISSN (Print) 0939-5075, DOI: https://doi.org/10.1515/znc-2017-0150.

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