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Zeitschrift für Physikalische Chemie

International journal of research in physical chemistry and chemical physics

Editor-in-Chief: Rademann, Klaus


IMPACT FACTOR 2018: 0.975
5-year IMPACT FACTOR: 1.021

CiteScore 2018: 1.20

SCImago Journal Rank (SJR) 2018: 0.327
Source Normalized Impact per Paper (SNIP) 2018: 0.391

Online
ISSN
2196-7156
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Volume 228, Issue 10-12

Issues

High Pressure X-ray Studies of Lipid Membranes and Lipid Phase Transitions

Nicholas J. Brooks
  • Corresponding author
  • Membrane Biophysics Platform and Institute of Chemical Biology, Department of Chemistry, Imperial College London, South Kensington Campus, London SW7 2AZ, UK
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  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ John M. Seddon
  • Membrane Biophysics Platform and Institute of Chemical Biology, Department of Chemistry, Imperial College London, South Kensington Campus, London SW7 2AZ, UK
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
Published Online: 2014-11-07 | DOI: https://doi.org/10.1515/zpch-2014-0602

Abstract

Hydrostatic pressure has dramatic effects on biomembrane structure and stability and is a key thermodynamic parameter in the context of the biology of deep sea organisms. Furthermore, high-pressure and pressure-jump studies are very useful tools in biophysics and biotechnology, where they can be used to study the mechanism and kinetics of lipid phase transitions, biomolecular transformations, and protein folding/unfolding. Here, we first give an overview of the technology currently available for X-ray scattering studies of soft matter systems under pressure. We then illustrate the use of this technology to study a variety of lipid membrane systems.

Keywords: Lipid Membranes; Hydrostatic Pressure; X-ray Diffraction; Lyotropic Phases

About the article

Accepted: 2014-10-12

Received: 2014-08-31

Published Online: 2014-11-07

Published in Print: 2014-12-28


Citation Information: Zeitschrift für Physikalische Chemie, Volume 228, Issue 10-12, Pages 987–1004, ISSN (Online) 2196-7156, ISSN (Print) 0942-9352, DOI: https://doi.org/10.1515/zpch-2014-0602.

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©2014 Walter de Gruyter Berlin/Boston.Get Permission

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