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Zeitschrift für Physikalische Chemie

International journal of research in physical chemistry and chemical physics

Editor-in-Chief: Rademann, Klaus


IMPACT FACTOR 2018: 0.975
5-year IMPACT FACTOR: 1.021

CiteScore 2018: 1.20

SCImago Journal Rank (SJR) 2018: 0.327
Source Normalized Impact per Paper (SNIP) 2018: 0.391

Online
ISSN
2196-7156
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Volume 228, Issue 4-5

Issues

Crystallization Behavior of Carbamazepine

Lisa Tröbs
  • BAM Federal Institute for Materials Research and Testing, Richard-Willstätter-Str. 11, 12489 Berlin, Germany
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/ Yen Nguyen Thi
  • BAM Federal Institute for Materials Research and Testing, Richard-Willstätter-Str. 11, 12489 Berlin, Germany
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/ Doreen Rump
  • BAM Federal Institute for Materials Research and Testing, Richard-Willstätter-Str. 11, 12489 Berlin, Germany
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/ Franziska Emmerling
  • Corresponding author
  • BAM Federal Institute for Materials Research and Testing, Richard-Willstätter-Str. 11, 12489 Berlin
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Published Online: 2014-02-24 | DOI: https://doi.org/10.1515/zpch-2013-0452

Abstract

Carbamazepine (CBZ) is known for its variety of anhydrous and hydrous polymorphs. Herein, a thorough analysis of the crystallization behavior of CBZ is presented. The influence of the solvent and the concentration on the crystallization behavior under different environmental conditions is investigated by combined in situ XRD and Raman spectroscopy measurements. Crystallization studies conducted via conventional crystallization in glass tubes and in levitated droplets using an acoustic levitator indicate a dependence of the crystallization process from solvent and surface.

Keywords: Carbamazepine; Polymorphism; Acoustic Levitation; XRD; Raman Spectroscopy

About the article

Accepted: 2014-02-07

Received: 2013-09-27

Published Online: 2014-02-24

Published in Print: 2014-05-28


Citation Information: Zeitschrift für Physikalische Chemie, Volume 228, Issue 4-5, Pages 493–501, ISSN (Online) 2196-7156, ISSN (Print) 0942-9352, DOI: https://doi.org/10.1515/zpch-2013-0452.

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