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Zeitschrift für Physikalische Chemie

International journal of research in physical chemistry and chemical physics

Editor-in-Chief: Rademann, Klaus

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Volume 231, Issue 3


Concept of Phase Cycling in Pulsed Magnetic Resonance Using Sinusoidal Magnetic Field Modulation

Mark Tseytlin
  • Corresponding author
  • Department of Biochemistry, School of Medicine, West Virginia University, Morgantown, West Virginia, United States of America
  • Center for EPR Imaging In Vivo Physiology, Department of Radiation and Cellular Oncology, University of Chicago, IL, United States of America
  • In vivo Multifunctional Magnetic Resonance center, Robert C. Byrd Health Sciences Center, West Virginia University, Morgantown, WV, United States of America
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Published Online: 2016-11-09 | DOI: https://doi.org/10.1515/zpch-2016-0843


In conventional pulsed magnetic resonance suppression of unwanted signals is achieved by changing pulse phases with respect to the reference signal and spin magnetization phase. This method is called phase cycling. An alternative approach is suggested to separate the unwanted signals from the spin echo by using magnetic field modulation. Precession frequency of the spins, and therefore phases of free indication decays and echo signals, can be controlled by the selection of modulation parameters. This enables phase cycling. Since the signal is detected in the presence of the changing magnetic field, which drives spin precession, the echo signal is frequency-modulated. Numerical transformation into an accelerating reference frame associated with the Larmor frequency restores the signal to a form that would have been observed in the absence of modulation. The suggested phase cycling method is analyzed in detail for the two pulse spin echo case.

Keywords: electron paramagnetic resonance; field modulation; phase cycling; pulsed magnetic resonance; rapid scan EPR

Dedicated to: Kev Salikhov on the occasion of his 80th birthday.


  • 1.

    J. Keeler, Understanding NMR spectroscopy, 2nd ed, Wiley, Chichester (2010), P. 511S.Google Scholar

  • 2.

    A. Schweiger, G. Jeschke, Principles of pulse electron paramagnetic resonance, Oxford University Press, Oxford (2001).Google Scholar

  • 3.

    S. K. Rengan, V. R. Bhagat, V. S. Suryanarayana Sastry, B. Venkataraman, J. Magn. Reson. 33 (1979) 227.Google Scholar

  • 4.

    J. P. Hornak, J. H. Freed, Chem. Phys. Letters 101 (1983) 115.Google Scholar

  • 5.

    G. G. Maresch, M. Weber, A. A. Dubinskii, H. W. Spiess, Chem. Phys. Letters 193 (1992) 134.Google Scholar

  • 6.

    J. W. Saalmueller, H. W. Long, T. Volkmer, U. Wiesner, G. G. Maresch, H. W. Spiess, J. Polym. Sci. Part B Polym Phys. 34 (1996) 1093.Google Scholar

  • 7.

    J. W. Saalmueller, H. W. Long, G. G. Maresch, H. W. Spiess, J. Magn. Reson. Series A. 117 (1995) 193.Google Scholar

  • 8.

    S. A. Dzuba, E. S. Salnikov, L. V. Kulik, Appl. Magn. Reson. 30 (2006) 637.Google Scholar

  • 9.

    L. V. Kulik, Y. A. Grishin, S. A. Dzuba, I. A. Grigoryev, S. V. Klyatskaya, S. F. Vasilevsky, Y. D. Tsvetkov, J. Magn. Reson. 157 (2002) 61.Google Scholar

  • 10.

    J. S. Hyde, J. C. W. Chien, J. H. Freed, J. Chem. Phys. 48 (1968) 4211.Google Scholar

  • 11.

    I. Tkach, G. Sicoli, C. Höbartner, M. Bennati, J. Magn. Reson. 209 (2011) 341.Google Scholar

  • 12.

    A. A. Dubinskii, Yu. A. Grishin, A. N. Savitsky, K. Möbius, Appl. Magn. Reson. 22 (2002) 369.Google Scholar

  • 13.

    R.-A. Eichel, A. Schweiger, J. Magn. Reson. 152 (2001) 276.Google Scholar

  • 14.

    R.-A. Eichel, A. Schweiger, Chem. Phys. Lett. 358 (2002) 271.Google Scholar

  • 15.

    R. K. Gupta, J. A. Ferretti, E. D. Becker, J. Magn. Reson. 13 (1974) 275.Google Scholar

  • 16.

    J. Dadok, R. F. Sprecher, J. Magn. Reson. 13 (1974) 243.Google Scholar

  • 17.

    M. Tseitlin, G. A. Rinard, R. W. Quine, S. S. Eaton, G. R. Eaton, J. Magn. Reson. 208 (2011) 279.Google Scholar

  • 18.

    D. Marsh, J. Magn. Reson. 248 (2014) 66.Google Scholar

  • 19.

    O. H. Griffith, A. S. Waggoner, Acc. Chem. Res. 2 (1969) 17.Google Scholar

  • 20.

    B. Epel, H. J. Halpern, J. Magn. Reson. 254 (2015) 56.Google Scholar

  • 21.

    M. Fedin, M. Kalin, I. Gromov, A. Schweiger, J. Chem. Phys. 120 (2004) 1361.Google Scholar

  • 22.

    M. Kalin, I. Gromov, A. Schweiger, Phys. Rev. A 69 (2004) 033809.Google Scholar

  • 23.

    I. Gromov, A. Schweiger, J. Magn. Reson. 146 (2000) 110.Google Scholar

  • 24.

    D. G. Mitchell, R. W. Quine, M. Tseitlin, S. S. Eaton, G. R. Eaton, J. Magn. Reson. 214 (2012) 221.Google Scholar

  • 25.

    D. G. Mitchell, R. W. Quine, M. Tseitlin, V. Meyer, SS. Eaton, G. R. Eaton, Radiat. Meas. 46 (2011) 993.Google Scholar

  • 26.

    D. G. Mitchell, G. M. Rosen, M. Tseitlin, B. Symmes, S. S. Eaton, G. R. Eaton, Biophys. J. 105 (2013) 338.Google Scholar

  • 27.

    D. G. Mitchell, M. Tseitlin, R. W. Quine, V. Meyer, M. E. Newton, A. Schnegg, B. George, S. S. Eaton, G. R. Eaton, Mol. Phys. 111 (2013) 2664.Google Scholar

  • 28.

    W. Froncisz, T. G. Camenisch, J. J. Ratke, J. R. Anderson, W. K. Subczynski, R. A. Strangeway, J. W. Sidabras, J. S. Hyde. J. Magn. Reson. 193 (2008) 297.Google Scholar

About the article

Corresponding author: Mark Tseytlin, Assistant Professor, Department of Biochemistry, School of Medicine, West Virginia University, Morgantown, West Virginia, USA, Tel.: +304-293-6425

Received: 2016-07-01

Accepted: 2016-10-10

Published Online: 2016-11-09

Published in Print: 2017-03-01

Citation Information: Zeitschrift für Physikalische Chemie, Volume 231, Issue 3, Pages 689–703, ISSN (Online) 2196-7156, ISSN (Print) 0942-9352, DOI: https://doi.org/10.1515/zpch-2016-0843.

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