Epidemiology of Toxoplasma gondii infection in native Tibetans in Tibet, China

Kun Li 1 , Meng Wang 1 , Hui Zhang 1 , Zhixin Lei 1 , Lihong Zhang 1 , Houqiang Luo 1 , Gang Qiu 1 , 2 , Khalid Mehmood 1 , 3 , Muhammad Shahzad 1 , 3  and Jiakui Li 1 , 2
  • 1 College of Veterinary Medicine, 430070, Wuhan, China
  • 2 Laboratory of Detection and Monitoring of Highland Animal Disease, Linzhi 860000, Tibet, China
  • 3 University College of Veterinary & Animal Sciences, Bahawalpur, Pakistan
Kun Li
  • College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, 430070, China
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, Meng Wang
  • College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, 430070, China
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, Hui Zhang
  • College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, 430070, China
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, Zhixin Lei
  • College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, 430070, China
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, Lihong Zhang
  • College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, 430070, China
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, Houqiang Luo
  • College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, 430070, China
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, Gang Qiu
  • College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, 430070, China
  • Laboratory of Detection and Monitoring of Highland Animal Disease, Tibet Agriculture and Animal Husbandry College, Linzhi 860000, Tibet, China
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, Khalid Mehmood
  • College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, 430070, China
  • University College of Veterinary & Animal Sciences, the Islamia University of Bahawalpur, Bahawalpur, Pakistan
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, Muhammad Shahzad
  • College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, 430070, China
  • University College of Veterinary & Animal Sciences, the Islamia University of Bahawalpur, Bahawalpur, Pakistan
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and Jiakui Li
  • Corresponding author
  • College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, 430070, China
  • Laboratory of Detection and Monitoring of Highland Animal Disease, Tibet Agriculture and Animal Husbandry College, Linzhi 860000, Tibet, China
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Abstract

Toxoplasma gondii (T. gondii) is one of the most common and widespread protozoan parasite which caused toxoplasma infection in animals and humans. Toxoplasma infection in healthy people is usually asymptomatic and it can lead to serious pathological effects in congenital cases and immunodeficient patients. The aim of the study is to investigate the prevalence of T. gondii infection in native Tibetans in Tibet as scarce information is available on such a high plateau. A total of 600 blood samples were collected from Tibetans people who visited the hospital in Nyingchi city with the history of flu, swollen lymph glands, muscle pain, and neurological or eyes complications (showing single or more signs). The serum of collected samples were tested for IgG antibody by ELISA. The result showed that the prevalence in men and women were 11.3% and 11.0%, respectively, the prevalence in different ages were 9.8% in < 7 years, 6.2% in ≥7–17 years, 10.1% in ≥18–40 years, 14.8% in ≥41–65 years and 11.6% in ≥66 years. The current study indicates the first report of this zoonotic parasite infection in Tibetan people.

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