Impact of the routine implementation of automated indirect immunofluorescence antinuclear antibody analysis: 1 year of experience

Sylvie M.N. Mulliez 1 , Thomas M. Maenhout 1 , and Carolien Bonroy 1
  • 1 Department of Clinical Chemistry, Microbiology and Immunology, Ghent University Hospital, Ghent, Belgium
Sylvie M.N. Mulliez, Thomas M. Maenhout and Carolien Bonroy

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    Agmon-Levin N, Damoiseaux J, Kallenberg C, Sack U, Witte T, Herold M, et al. International recommendations for the assessment of autoantibodies to cellular antigens referred to as anti-nuclear antibodies. Ann Rheum Dis 2014;73:17–23.

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    Bonroy C, Verfaillie C, Smith V, Persijn L, De Witte E, De Keyser F, et al. Automated indirect immunofluorescence antinuclear antibody analysis is a standardized alternative for visual microscope interpretation. Clin Chem Lab Med 2013;51:1771–9.

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  • 4.

    Bossuyt X, Cooreman S, De Baere H, Verschueren P, Westhovens R, Blockmans D, et al. Detection of antinuclear antibodies by automated indirect immunofluorescence analysis. Clin Chim Acta 2013;415:101–6.

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  • 5.

    Bizzaro N, Antico A, Platzgummer S, Tonutti E, Bassetti D, Pesente F, et al. Automated antinuclear immunofluorescence antibody screening: a comparative study of six computer-aided diagnostic systems. Autoimmun Rev 2014;13:292–8.

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  • 6.

    Maenhout TM, Bonroy C, Verfaillie C, Stove V, Devreese K. Automated indirect immunofluorescence microscopy enables the implementation of a quantitative internal quality control system for anti-nuclear antibody (ANA) analysis. Clin Chem Lab Med 2014;52:989–98.

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