Imaging of the human tympanic membrane by endoscopic optical coherence tomography

Martin Schindler 1 , Lars Kirsten 2 , Joseph Morgenstern 3 , Jonas Golde 2 , Mikael Erkkilä 4 , Julia Walther 5 , Max Kemper 3 , Matthias Bornitz 3 , Marcus Neudert 3 , Thomas Zahnert 3  and Edmund Koch 6
  • 1 TU Dresden, Faculty of Medicine Carl Gustav Carus, Anesthesiology and Critical Care Medicin, Clinical Sensoring and Monitoring, Fetscherstr. 74, 01307, Dresden, Germany
  • 2 TU Dresden, Faculty of Medicine Carl Gustav Carus, Anesthesiology and Critical Care Medicin, Clinical Sensoring and Monitoring, 01307, Dresden, Germany
  • 3 TU Dresden, Faculty of Medicine Carl Gustav Carus, Otorhinolaryngology, 01307, Dresden, Germany
  • 4 Medical University of Vienna, Center for Medical Physics and Biomedical Engineering, A-1090, Vienna, Austria
  • 5 TU Dresden, Faculty of Medicine Carl Gustav Carus, Anesthesiology and Critical Care Medicin, Clinical Sensoring and Monitoring/Medical Physics and Biomedical Engineering, 01307, Dresden, Germany
  • 6 TU Dresden, Faculty of Medicine Carl Gustav Carus, Anesthesiology and Critical Care Medicin, Clinical Sensoring and Monitoring, 01307, Dresden, Germany

Abstract

Endoscopic optical coherence tomography is a non-invasive and contactless imaging technique based on white light interferometry. It enables high-resolution three-dimensional imaging of scattering tissue up to a depth of about 2 mm. In addition, Doppler-OCT can detect sub-resolution movements. These features can be used to examine the tympanic membrane, the surrounding tissue and nearby areas of the tympanic cavity. For this purpose, we present an endoscopic OCT system, which provides access to the tympanic membrane. The design of the endoscope is based on a gradientindex (GRIN) lens system. This allows a broad field of view and a large working distance. An additional VIS beam path allows visual imaging and orientation inside the auditory canal. Therefore, illumination fibers are attached a round the GRIN-system. The resulting endoscope has a length of 55 mm and a diameter of 3.5 mm. By attaching an earphone and a probe microphone, the oscillation of the tympanic membrane can be measured under acoustic stimulation. With the endoscopic OCT system, we provide an examination tool for the diagnosis of a broad number of diseases like conductive hearing loss.

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Current Directions in Biomedical Engineering is an open access journal and closely related to the journal Biomedical Engineering - Biomedizinische Technik. CDBME is a forum for the exchange of knowledge in the fields of biomedical engineering, medical information technology and biotechnology/bioengineering for medicine and addresses engineers, natural scientists, and clinicians working in research, industry, or clinical practice.

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