Synthesis and stereochemistry of some new 1,3,5-tris(1,3-dioxan-2-yl)-benzene derivatives

Maria Florian, Monica Cîrcu 1 , Loïc Toupet 2 , Anamaria Terec 1 , Ion Grosu 1 , Yvan Ramondenc 3 , Nicolae Dincă 4 , and Gerard Plé 3
  • 1 Organic Chemistry Department and CCOCCAN, “Babes-Bolyai” University, 400028, Cluj-Napoca, Romania
  • 2 UMR C 6626, Université de Rennes I, 35042, Rennes, Cedex, France
  • 3 IRCOF, UMR 6014, Faculté des Sciences de Rouen, Université de Rouen, 76821, Mont Saint Aignan, Cedex, France
  • 4 Faculty of Engineering, “Aurel Vlaicu” University, 310025, Arad, Romania


The synthesis and the stereochemistry of new 1,3,5-tris(1,3-dioxan-2-yl)-benzene derivatives are reported. The anancomeric structure and the axial orientation of the aryl group with respect to all 1,3-dioxane rings, and the cis-trans isomerism of some of the compounds are revealed. The data are supported by NMR investigations and by the molecular structure of one compound determined by single crystal X-ray diffractometry.

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