HERBAVATE is a topical preparation that contains the oil extracts of Calotropis gigantea, Curcuma longa, Pongamia glabra & Solanum xanthocarpum in a cream base. The present study is a pilot study evaluating the efficacy and safety of HERBAVATE in the management of eczema.37 out-patients with a clinical diagnosis of eczema were enrolled in an open label study carried out at 2 centers. Patients applied HERBAVATE cream over the lesion twice daily and were followed up weekly for 4 weeks. Patients were assessed weekly on a 4 point scale for the severity of symptoms associated with eczema, viz. erythema, scaling, lichenification and pruritis. Local tolerance was assessed on a 4 point scale.All analysis were carried out on 32 patients, there were 5 dropouts. At the end of the study there was a significant fall in the mean scores for erythema, scaling, lichenification and pruritis. HERBAVATE was well tolerated with only 2 patients reporting mild burning at site of application which improved with continued application.HERBAVTE appears to an attractive alternate option for the management of eczema. However, larger studies of longer duration are needed.
The Journal of Complementary and Integrative Medicine focuses on evidence concerning the efficacy and safety of complementary and alternative medical (CAM) whole systems, practices, interventions and natural health products, including herbal medicines.