Premature thelarche related to fennel tea consumption?

Deniz Okdemir 1 , Nihal Hatipoglu 1 , Selim Kurtoglu 1 , Leyla Akın 1 , and Mustafa Kendirci 1
  • 1 Faculty of Medicine, Department of Pediatric Endocrinology, Erciyes University, Kayseri, Turkey
Deniz Okdemir, Nihal Hatipoglu, Selim Kurtoglu, Leyla Akın and Mustafa Kendirci

Abstract

Background: Isolated premature thelarche is the breast development in the absence of other secondary sex characteristics in prepubertal girls. Fennel is a plant which contains a phytoestrogen called anethole as an active ingredient.

Case: Here, we report a case of a 12-month-old girl who showed breast development that became apparent in the last 3 months. Her medical history revealed that she was given two to three teaspoons of fennel tea by her mother every day for restlessness for the last 6 months. Isolated premature thelarche was diagnosed based on physical and laboratory findings. On follow-up, after cessation of fennel consumption, the breast development of the patient regressed gradually and became normal by the end of 1 year.

Conclusion: Reporting this case, we want to emphasize the importance of awareness of fennel tea, a commonly used plant in babies, as a preventable cause of premature thelarche.

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