Identifying depressive symptoms among diabetes type and the impact on hemoglobin A1c

Bethany A. Glick 1 , K. Ming Chan Hong 1 , Kathryn Obrynba 1 , Manmohan K. Kamboj 1  and Robert P. Hoffman 1
  • 1 Nationwide Children’s Hospital, Pediatric Endocrinology, 700 Children’s Drive, Columbus, OH, USA
Bethany A. Glick
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  • Nationwide Children’s Hospital, Pediatric Endocrinology, 700 Children’s Drive, Columbus, OH, USA
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, K. Ming Chan Hong
  • Nationwide Children’s Hospital, Pediatric Endocrinology, 700 Children’s Drive, Columbus, OH, USA
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, Kathryn Obrynba
  • Nationwide Children’s Hospital, Pediatric Endocrinology, 700 Children’s Drive, Columbus, OH, USA
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, Manmohan K. Kamboj
  • Nationwide Children’s Hospital, Pediatric Endocrinology, 700 Children’s Drive, Columbus, OH, USA
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and Robert P. Hoffman
  • Nationwide Children’s Hospital, Pediatric Endocrinology, 700 Children’s Drive, Columbus, OH, USA
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Abstract

Background:

This study was designed to determine the effects of diabetes type and gender on depression risk determined by a highly sensitive screening questionnaire in adolescents. Glycemic control and counseling affect were also studied.

Methods:

A retrospective chart review of patients seen between 2013 and 2015 was performed. Five hundred and thirty adolescents with type 1 (T1DM) or 2 (T2DM) diabetes mellitus completed the Patient Health Questionnaire-9 (PHQ-9) to identify depressive symptoms. Hemoglobin A1c (HbA1c) was measured when the PHQ-9 was given, and at 1 year. Patients with increased depression risk were referred for counseling and comparisons were made between those who did and did not attend.

Results:

Females with T2DM, but not males, had increased depression compared to T1DM. Females had increased depression compared to males in T1DM (p = 0.046) and a near significant increase in T2DM (p = 0.069). In T1DM, but not T2DM, HbA1c levels were increased in high and moderate, compared to low, risk depression risk groups (p = 0.007). Follow-up HbA1c was unchanged 1 year later and there were no differences between those involved in counseling and those who refused to attend. Sex and type of diabetes had no effect on response to counseling.

Conclusions:

These results demonstrate increased depression in adolescents with T2DM compared to T1DM and in females compared to controls. Glycemic control did not change in adolescents who reported moderate to severe symptoms of depression and received counseling intervention compared to adolescents who declined counseling.

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The Journal of Pediatric Endocrinology and Metabolism (JPEM) is the only international journal dedicated exclusively to endocrinology in the neonatal, pediatric and adolescent age groups, and publishes the results of clinical investigations in pediatric endocrinology and basic research. JPEM publishes Review Articles, Original Research, Case Reports, Short Communications and Letters to the Editor.

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