Inclusion body myositis — a case based clinicopathological update

Levente Bodoki 1 , Melinda Vincze 1 , Zoltán Griger 1 , Tamás Csonka 2 , Balázs Murnyák 2 , Andrea Kurucz 2 , Katalin Dankó 1 , and Tibor Hortobágyi 2
  • 1 Institute of Internal Medicine, Third Department of Internal Medicine, Division of Clinical Immunology, University of Debrecen Medical & Health Science Centre, Debrecen, Hungary
  • 2 Institute of Pathology, Department of Neuropathology, University of Debrecen Medical and Health Science Centre, Debrecen, Hungary

Abstract

Inclusion body myositis is a slowly progressive myopathy affecting predominantly the middle-aged and older patient population. It is a major form of the idiopathic inflammatory myopathies which are chronic systemic autoimmune diseases characterized by symmetrical proximal muscle weakness. Unfortunately, there is no effective therapy yet; however, the early diagnosis is essential to provide treatment options which may significantly slow the progression of the disease. In our case-based clinicopathological study the importance of the close collaboration between the clinician and the neuropathologist is emphasised.

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