Application of Food-specific IgG Antibody Detection in Allergy Dermatosis

Hu Yine 1 , Dai Shufang 2 , Wang Bin 2 , Qu Wei 2 , Muhammad Aqeel Ashraf 2  and Gao Junling 2
  • 1 Dermatological Department of Huaihe Hospital of Henan University in Kaifeng, Henan 475000, Tel: 139-3860-4120
  • 2 Huaihe Hospital of Henan University, Henan, China


The application of food-specific IgG antibody detection in allergy dermatoses was explored. 181 patients with allergy dermatoses were diagnosed from January to September 2014 and 20 healthy subjects were selected. Fourteen kinds of food-specific IgG antibodies were detected by ELISA method among all the subjects. The positive rates of IgG antibody of the patient group and the healthy group were respectively 65.2% and 5.0%. The positive rates of IgG antibody of egg, milk, shrimp and crab took a large proportion in three groups of patients with three kinds of allergy dermatoses of urticaria, eczema and allergic dermatitis, the proportion of which was respectively 70.2%, 77.8% and 71.7%. Among urticaria and allergic dermatitis patients with positive antibody, the positive rate of children was significantly higher than that of adults (p<0.05) while there was no significant difference between children and adults among eczema patients with positive antibody (p>0.05). Allergy dermatoses are closely related to food-specific IgG antibodies, and the allergy dermatoses patients have a high incidence rate of food intolerance; detecting IgG antibody in the serum of patients is of great significance for the diagnosis and treatment of allergy dermatoses.

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  • [1] Yalan D., Tianjian Y., Donghua C., et al., Study on the correlation between food intolerance and allergy dermatoses, International Journal of Laboratory Medicine, 2013, 34(4), 496-498

  • [2] Yan S., Ying J., Hongjuan W., et al., Detection result analysis of food intolerance of 3 common skin diseases patients, China journal of leprosy and skin deseases, 2013, (9), 617-618

  • [3] Hui L., Clinical observation of food intolerance Igg antibody of allergy dermatoses. Clinical Focus, 2011, 26(14), 1256-1257

  • [4] Bergmann M.M., Caubet J.C., Boguniewicz M., et al., Evaluation of food allergy in patients with atopic dermatitis, The journal of allergy and clinical immunology: In Practice, 2013, 1(1), 22-28

  • [5] Werfel T., Breuer K., Role of food allergy in atopic dermatitis, Current opinion in allergy and clinical immunology, 2004, 4(5), 379-385

  • [6] Chafen J.J.S., Newberry S.J., Riedl M.A., et al., Diagnosing and managing common food allergies: a systematic review, Jama, 2010, 303(18), 1848-1856

  • [7] Zhiping X., Renshan Z., Rong W., et al., correlation analysis of allergy dermatoses and food-specific igg antibody, Journal of diagnosis and therapy on dermato-venereology, 2013, (4), 274-276

  • [8] Tingzheng H., Xiaogang L., Observation And Analysis of Detection Result of Food Intolerance Igg Antibody, Laboratory Medicine and Clinic, 2011, 08(14), 1766-1767

  • [9] Hongyun Z., Wuzhong Y., Huiwu W., et al., Application of Food-Specific IgG antibody detection in the allergy dermatoses, China journal of modern medicine, 2010, 20(16), 2471-2474

  • [10] Weixin F., Yeqin D., Correlation research of food intolerance and skin diseases, Proceedings of the national Chinese medicine dermatology conference, 2007, 19-22

  • [11] Songjiang W., Zhijun L., Result analysis of food intolerance of 3 allergy dermatoses patients, Guide of China Medicine, 2012, (32), 464-466

  • [12] Rowntree S., Cogswell J.J., Platts-Mills T.A., et al., Development of IgE and IgG antibodies to food and inhalant allergens in children at risk of allergic disease, Archives of disease in childhood, 1985, 60(8), 727-735

  • [13] Sicherer S.H., Sampson H.A., Food allergy, Journal of allergy and clinical immunology, 2010, 125(2), S116-S125

  • [14] Burks A., Tang M., Sicherer S., et al., ICON, food allergy, Journal of Allergy and Clinical Immunology, 2012, 129(4), 906-920

  • [15] Nowak-Węgrzyn A., Sampson H.A., Future therapies for food allergies, Journal of allergy and clinical immunology, 2011, 127(3), 558-573


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