Data collection and handling.
| Crystal: | Parallelpiped |
| Size: | 0.20 × 0.20 × 0.10 mm |
| Wavelength: | Synchrotron radiation (0.9699 Å) |
| μ: | 0.25 mm−1 |
| Diffractometer, scan mode: | Synchrotron Radiation, ϕ-scan |
| θmax, completeness: | 38.5°, 97% |
| N(hkl)measured, N(hkl)unique, Rint: | 21424, 4031, 0.074 |
| Criterion for Iobs, N(hkl)gt: | Iobs > 2 σ(Iobs), 2857 |
| N(param)refined: | 277 |
| Programs: | Olex2 [14] |
The asymmetric unit of the title crystal structure is shown in the figure. Tables 1 and 2 contain details on crystal structure and measurement conditions and a list of the atoms including atomic coordinates and displacement parameters.
Fractional atomic coordinates and isotropic or equivalent isotropic displacement parameters (Å2).
| Atom | x | y | z | Uiso*/Ueq |
|---|---|---|---|---|
| O1 | 0.53895(17) | 0.50371(13) | 0.14659(14) | 0.0272(5) |
| O2 | 0.66863(17) | 0.39465(12) | 0.32594(14) | 0.0272(5) |
| O3 | 0.41410(18) | 0.34009(12) | 0.36896(15) | 0.0320(5) |
| O4 | 0.30855(18) | 0.42559(13) | 0.19913(15) | 0.0327(5) |
| O5 | 0.92773(19) | 0.51245(14) | 0.25445(17) | 0.0359(5) |
| O6 | 0.86050(18) | 0.66528(13) | 0.26739(17) | 0.0347(5) |
| O7 | 0.84057(18) | 0.66491(13) | 0.47755(16) | 0.0360(6) |
| O8 | 0.65940(17) | 0.73253(12) | 0.38401(14) | 0.0288(5) |
| C1 | 0.5929(3) | 0.48200(19) | 0.4394(2) | 0.0269(7) |
| H1A | 0.595130 | 0.420758 | 0.482900 | 0.032* |
| H1B | 0.607045 | 0.540190 | 0.491118 | 0.032* |
| N2 | 0.4770(2) | 0.49140(15) | 0.33724(18) | 0.0258(6) |
| C3 | 0.4601(3) | 0.57971(18) | 0.2638(2) | 0.0276(7) |
| H3A | 0.463968 | 0.640920 | 0.308017 | 0.033* |
| H3B | 0.381142 | 0.576736 | 0.195366 | 0.033* |
| C3A | 0.5521(3) | 0.58553(18) | 0.2237(2) | 0.0248(6) |
| C4 | 0.5559(3) | 0.67432(19) | 0.1512(2) | 0.0289(7) |
| H4 | 0.526204 | 0.739848 | 0.148393 | 0.035* |
| C5 | 0.6094(3) | 0.6401(2) | 0.0933(2) | 0.0306(7) |
| H5 | 0.627273 | 0.676562 | 0.041309 | 0.037* |
| C6 | 0.6365(3) | 0.5299(2) | 0.1269(2) | 0.0283(7) |
| H6 | 0.645004 | 0.487444 | 0.068482 | 0.034* |
| C6A | 0.7430(3) | 0.52286(18) | 0.2548(2) | 0.0249(6) |
| C7 | 0.7680(3) | 0.41286(18) | 0.3066(2) | 0.0277(7) |
| H7 | 0.780470 | 0.361709 | 0.257709 | 0.033* |
| C8 | 0.8675(3) | 0.42068(17) | 0.4315(2) | 0.0262(6) |
| H8 | 0.947277 | 0.401213 | 0.460299 | 0.031* |
| C9 | 0.8177(3) | 0.46082(17) | 0.4912(2) | 0.0249(6) |
| H9 | 0.854880 | 0.476216 | 0.571544 | 0.030* |
| C9A | 0.6887(3) | 0.47681(17) | 0.4033(2) | 0.0235(6) |
| C9B | 0.6833(2) | 0.56946(17) | 0.3239(2) | 0.0234(6) |
| C10 | 0.4013(3) | 0.41226(18) | 0.3062(2) | 0.0253(6) |
| C11 | 0.2027(3) | 0.3614(2) | 0.1565(2) | 0.0298(7) |
| C12 | 0.2313(3) | 0.2527(2) | 0.1461(3) | 0.0422(8) |
| H12A | 0.272911 | 0.248818 | 0.099988 | 0.063* |
| H12B | 0.158281 | 0.214061 | 0.107969 | 0.063* |
| H12C | 0.281257 | 0.225310 | 0.223532 | 0.063* |
| C13 | 0.1456(3) | 0.3743(2) | 0.2347(3) | 0.0371(8) |
| H13A | 0.199281 | 0.349841 | 0.312616 | 0.056* |
| H13B | 0.072150 | 0.336168 | 0.202910 | 0.056* |
| H13C | 0.128905 | 0.445317 | 0.238635 | 0.056* |
| C14 | 0.1251(3) | 0.4053(3) | 0.0365(3) | 0.0463(9) |
| H14A | 0.108058 | 0.475482 | 0.044112 | 0.069* |
| H14B | 0.051330 | 0.367574 | −0.001534 | 0.069* |
| H14C | 0.166119 | 0.400875 | −0.010054 | 0.069* |
| C15 | 0.8531(3) | 0.56548(19) | 0.2600(2) | 0.0280(7) |
| C16 | 0.9690(3) | 0.7089(2) | 0.2794(3) | 0.0386(8) |
| H16A | 0.969886 | 0.705079 | 0.205033 | 0.058* |
| H16B | 1.036385 | 0.672011 | 0.338315 | 0.058* |
| H16C | 0.973921 | 0.779088 | 0.302933 | 0.058* |
| C17 | 0.7392(3) | 0.65990(17) | 0.4019(2) | 0.0247(6) |
| C18 | 0.7011(3) | 0.81678(19) | 0.4637(2) | 0.0343(7) |
| H18A | 0.654694 | 0.876343 | 0.425467 | 0.051* |
| H18B | 0.784086 | 0.829329 | 0.486658 | 0.051* |
| H18C | 0.692729 | 0.801415 | 0.532610 | 0.051* |
Source of material
Synthesis and characterization by 1H/13C NMR, IR and HRMS methods was reported in [10], [11].
Experimental details
H atoms were located in the difference Fourier map, but refined with fixed individual displacement parameters, using a riding model with C—H distances of 0.95–1.0 Å (for aromatic rings), and C—H distances 0.99, 0.98 Å for methylene nd methyl groups, with U(H) values of 1.2Ueq(CAr and CH2) and 1.5Ueq(C) (for CH3).
Comment
Weak interactions, such as hydrogen, halogen, chalcogen, pnicogen, tetrel and icosagen bonds were extensively used in the synthesis, catalysis, crystal engineering, drug delivery, etc. [1], [2], [3], [4], [5]. Among those, hydrogen bonding has turned out to be particularly suitable for design of organic and coordination compounds [6], [7], [8], [9]. There is one title molecule in the asymmetric unit.
The molecule comprises a fused hexacyclic system containing four five-membered rings in the usual envelope conformations with Cremer and Pople parameters [12] ranging from (Q(2) = 0.517(3)–0.583(3) Å; φ2 = 175.2(3)–181.4(4)°) and one six-membered rings adopting a chair conformation with Cremer and Pople parameters Q = 0.523(3) Å, θ = 6.8(3)°, φ = 52(3)° respectively. In the crystal structure the molecules are linked at least by C—O⋯H intermolecular hydrogen bond which link molecules into centrosymmetric dimers with R22(10) graph-set notation [13]. Other weak intermolecular interactions will contibute to the stability of the packing. The carboxylate groups are α-oriented, meanwhile, the tert-butyl carboxylate group is β-oriented. All distances and angles are normal.
X-ray crystallographic studies using synchrotron radiation were performed at the unique scientific facility Kurchatov Synchrotron Radiation Source supported by the Ministry of Education and Science of the Russian Federation (project code RFMEFI61917X0007). This work has also been partially supported by Universidad de Antofagasta, and Baku State University.
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