Optofluidics for handling and analysis of single living cells

Gerardo Perozziello 1 , Patrizio Candeloro 1 , Maria Laura Coluccio 1 ,  and Enzo Di Fabrizio 2
  • 1 Nanotechnology laboratory (BIONEM), Department of Experimental and Clinical Medicine, University of Magna Graecia Viale Europa, Germaneto, , Catanzaro , Italy
  • 2 Physical Sciences and Engineering (PSE), King Abdullah University of Science and Technology (KAUST), , Thuwal , Kingdom of Saudi Arabia

Abstract

Optofluidics is a field with important applications in areas such as biotechnology, chemical synthesis and analytical chemistry. Optofluidic devices combine optical elements into microfluidic devices in ways that increase portability and sensitivity of analysis for diagnostic or screening purposes .In fact in these devices fluids give fine adaptability, mobility and accessibility to nanoscale photonic devices which otherwise could not be realized using conventional devices. This review describes several cases inwhich optical or microfluidic approaches are used to trap single cells in proximity of integrated optical sensor for being analysed.

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This is a peer-reviewed Open Access journal, devoted to the publication of research and applied data from the full spectrum of Optofluidics, Microfluidics and Nanofluidics; designed to facilitate the exchange of ideas between researchers and especially practitioners from different disciplines ranging from biology to chemistry to engineering.

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