Fibrinogen and cellular adherability on differently treated titanium as implants

Lukáš Fojt 1 , Petr Klapetek 2 , Luděk Strašák 1 , and Vladimír Vetterl 1
  • 1 Institute of Biophysics, Academy of Sciences of the Czech Republic, Královopolská 135, Brno, 612 65, Czech Republic
  • 2 Czech Metrology Institute, Okružní 31, Brno, 638 00, Czech Republic

Abstract

Adsorption of human plasma fibrinogen, osteoblasts, and fibroblasts on differently treated titanium samples as implants were examined in this study. Titanium samples were mechanically polished, chemically etched (with and without surface material loss), and grinded. The main goal of this study is to find the best surface treatment of titanium for its possible use as implants. Atomic force microscopy was used to evaluate the adsorption of human plasma fibrinogen onto the titanium samples. Cell counting was used to determine the adherability of osteoblasts and fibroblasts on the titanium samples. Our preliminary results show that the etched titanium surface with surface material loss is the best surface treatment used in our experiments.

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