On-chip redox cycling techniques for electrochemical detection

Enno Kätelhön and Bernhard Wolfrum
  • 1 Institute of Bioelectronics (ICS-8/PGI-8), Forschungszentrum Jülich GmbH, 52425 Jülich, Germany
  • 2 JARA, Fundamentals of Future Information Technology, Forschungszentrum Jülich GmbH, 52425 Jülich, Germany


During the last two decades, redox cycling techniques have evolved as a promising technique for the electrochemical detection of molecules that can undergo subsequent redox reactions. In particular, chip-based techniques received growing attention due to the option of parallel fabrication and easy integration into lab-on-a-chip devices. In here, we provide a review on current implementations of on-chip redox cycling sensors. Advantages and limitations of various approaches are discussed with regard to their fabrication process and performance.

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Reviews in Analytical Chemistry publishes authoritative reviews by leading experts in the dynamic field of chemical analysis. The subjects can encompass all branches of modern analytical chemistry such as spectroscopy, electrochemistry, chromatography, trace analysis and solution chemistry and their applications to areas such as environmental control, mineral resources, drug analysis, and other relevant areas.