Vergleich der Amino- und Hydroxy-Nachbargruppe bei Dehydrierungen.

Comparison between the Amino and the Hydroxy Neighbour Group in Dehydrogenation Reactions

H. Möhrle 1 , Chr. Kamper 1  and R. Feil 1
  • 1 Institut für Pharmazie der Freien Universität Berlin

The mercuric EDTA dehydrogenation of the isomeric 1,2- and 2,1-(phenyl-pyrrolidino)-ethanols yields with two electron removal the corresponding oxazolidines. The analogous 1,2- and 2,1-(amino-phenyl)pyrrolidines by double dehydrogenation produce the amidines resp. by subsequent hydrolysis the lactams. An explanation for the different course of the reaction is given

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Zeitschrift für Naturforschung B is an international scientific journal which publishes original papers, microreviews, and letters from all areas of inorganic chemistry, solid state chemistry, coordination chemistry, molecular chemistry, and organic chemistry.